Study the Signs of Ocular Degeneration in a Population Cohort (Dijon 3C Montrachet Cohort)

Not Applicable

Completed

• Conditions: Glaucoma; AMD

• Registration Number: NCT01766596
• Lead Sponsor: Centre Hospitalier Universitaire Dijon

Brief Summary

The aim of the study proposed in Dijon is above all to focus on the possible relationship between age-related ocular pathologies (AMD and glaucoma) and et les degenerative neurological and cardiac pathologies.

The principal objective is to seek in subjects who have undergone cerebral MRI and echocardiography, associations between the thickness of postganglionic fibers measured by Optical Coherence Tomography at the 7th year (n=1500) and signs of cerebral impairment (psycho-cognitive tests, circulation time, MRI signs). This association will be studied after taking into account the principal environmental (particularly dietary) and genetic risk factors.

Detailed Description

Not available

Study Timeline

• Study Start: 2009-10
• Study First Submitted: 2013-01-10
• Study First Submitted QC: 2013-01-10
• Study First Posted: 2013-01-11
• Primary Completion: 2013-10
• Study Completion: 2019-11-04
• Status Verified: 2024-04
• Last Update Submitted: 2024-04-30
• Last Update Posted: 2024-05-01

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 1153

Inclusion Criteria

• Persons who have given their written consent
• Persons who are taking part in the Dijon 3C study

Exclusion Criteria

• Persons who are not registered with social security agency
• Persons who are unable to sit upright during a consultation

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Measure the mean thickness of postganglionic fibers	T=7 years of the 3C cohort	Measure the thickness of postganglionic fibers by Optical Coherence Tomography in the 4 quadrants of the peripapillary sclera.

Trial Locations

Locations (1)

CHU Dijon; 🇫🇷 Dijon, France