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临床试验/ChiCTR-IPC-15007294
ChiCTR-IPC-15007294已完成不适用

應用雙側經顱磁刺激對中風後失語症康復的研究:從亞急性期到慢性期

Nil1 个研究点 分布在 1 个国家开始时间: 1990年1月1日最近更新:

试验速览

阶段
不适用
状态
已完成
发起方
试验地点
1
主要终点
changes in scores of language assessment, measured by Cantonese version of Western Aphasia Battery.

研究概览

简要总结

應用雙側經顱磁刺激對中風後失語症康復的研究:從亞急性期到慢性期

研究设计

研究类型
观察性研究
主要目的
非随机对照试验

入排标准

年龄范围
18 至 —(—)
性别
All

入选标准

  • aged 18 or above, right-handed, Cantonese native speaker;
  • first-ever ischemic stroke with onset time less than 21 days and left middle cerebral artery (LMCA) territory involved;
  • recordable motor evoked potential (MEP) in either hand;
  • mild to moderate motor-dominant aphasia (National Institution of Health Stroke Scale (NIHSS) Part 9 = 1);
  • capable of undergoing language assessment (NIHSS Part 1a=0, 1b=0 or 1 and 1c= 0 or 1);
  • the patient or his/her legally acceptable representative is willing to provide written informed consent.

排除标准

  • personal history of epilepsy;
  • metallic implants in any part of body;
  • implanted cardiac pacemaker, defibrillator, medication pump or any other implanted electronics;
  • severe skull fracture, serious head injury, history of brain or spinal cord surgery;
  • brain tumor on CT/MRI;
  • administration of drugs that potentially lower seizure threshold;
  • active malignancy;
  • severe co-existing systemic diseases, severe dementia or psychosis;
  • inability to be followed up at regular interval;
  • pregnancy or breast-feeding;
  • pure word deafness;
  • diagnosed dementia;
  • clinical evidence of depression;
  • clinical sign of hearing or visual impairment without aids;
  • alcohol abuse and drug addiction.

研究组 & 干预措施

Single arm

结局指标

主要结局

changes in scores of language assessment, measured by Cantonese version of Western Aphasia Battery.

次要结局

  • changes in sub AQs of CWAB measured by Cantonese version of Western Aphasia Battery.

研究者

发起方
Nil

研究点 (1)

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