ChiCTR-IPC-15007294已完成不适用
應用雙側經顱磁刺激對中風後失語症康復的研究:從亞急性期到慢性期
Nil1 个研究点 分布在 1 个国家开始时间: 1990年1月1日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 试验地点
- 1
- 主要终点
- changes in scores of language assessment, measured by Cantonese version of Western Aphasia Battery.
研究概览
简要总结
應用雙側經顱磁刺激對中風後失語症康復的研究:從亞急性期到慢性期
研究设计
- 研究类型
- 观察性研究
- 主要目的
- 非随机对照试验
入排标准
- 年龄范围
- 18 至 —(—)
- 性别
- All
入选标准
- •aged 18 or above, right-handed, Cantonese native speaker;
- •first-ever ischemic stroke with onset time less than 21 days and left middle cerebral artery (LMCA) territory involved;
- •recordable motor evoked potential (MEP) in either hand;
- •mild to moderate motor-dominant aphasia (National Institution of Health Stroke Scale (NIHSS) Part 9 = 1);
- •capable of undergoing language assessment (NIHSS Part 1a=0, 1b=0 or 1 and 1c= 0 or 1);
- •the patient or his/her legally acceptable representative is willing to provide written informed consent.
排除标准
- •personal history of epilepsy;
- •metallic implants in any part of body;
- •implanted cardiac pacemaker, defibrillator, medication pump or any other implanted electronics;
- •severe skull fracture, serious head injury, history of brain or spinal cord surgery;
- •brain tumor on CT/MRI;
- •administration of drugs that potentially lower seizure threshold;
- •active malignancy;
- •severe co-existing systemic diseases, severe dementia or psychosis;
- •inability to be followed up at regular interval;
- •pregnancy or breast-feeding;
- •pure word deafness;
- •diagnosed dementia;
- •clinical evidence of depression;
- •clinical sign of hearing or visual impairment without aids;
- •alcohol abuse and drug addiction.
研究组 & 干预措施
Single arm
结局指标
主要结局
changes in scores of language assessment, measured by Cantonese version of Western Aphasia Battery.
次要结局
- changes in sub AQs of CWAB measured by Cantonese version of Western Aphasia Battery.
研究者
研究点 (1)
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