跳至主要内容
临床试验/CTRI/2024/10/074733
CTRI/2024/10/074733招募中不适用

A Clinical study on the Effectiveness of Homoeopathic medicine Vanadium metallicum 6CH in the treatment of Iron deficiency anemia in Reproductive age group women

Vinayaka Missions Homoeopathic Medical College and Hospital1 个研究点 分布在 1 个国家目标入组 35 人开始时间: 2024年11月1日最近更新:

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
35
试验地点
1
主要终点
1. Increase in Blood Hb Concentration

研究概览

简要总结

Iron deficiency anemia arises when the balance of iron intake, iron stores, and the body's loss of

iron are insufficient to fully support production of erythrocytes. Iron deficiency anemia rarely

causes death, but the impact on human health is significant.

In the developed world, this disease is easily identified and treated, but frequently overlooked

by physicians. In contrast, it is a health problem that affects major portions of the population in

underdeveloped countries.

Overall, the prevention and successful treatment for iron deficiency anemia remains woefully

insufficient worldwide, especially among underprivileged women and children[1].Iron

deficiency can result in fatigue, poor concentration (brain fog), alopecia, ridged/brittle nails,

aching and restless legs, reduced exercise tolerance, anxiety, low mood/depression and poor

work performance. Cognitive decline has also been reported in elderly individuals. In severe

cases, pica – a craving and purposive consumption for non-food items such as ice (pagophagia)

and starch (amylophagia) may develop, especially in women whose serum ferritin

< 10 µg.l-1.[2]

Homoeopathic medicines are quite effective in management of iron deficiency anemia and the

remedies includes Ferrum phosphoricum, Arsenicum album, Apis mellifica,cinchona

officinalis, Vanadium, Gelsemium etc., Vanadium metallicum helps in the improvement of

appetite and body, strength, it has positive effects on nutritional anaemia it acts as an oxygen

carrier and catalyzer, it's increasing haemoglobin levels.[3]

Hence this study is to evaluate the effectiveness of homoeopathy medicine Vanadium

metallicum 6CH in treatment of iron deficiency anemia by increasing hemoglobin

concentration, mean corpuscular hemoglobin and serrum ferritin.

DRUG DESCRIPTION

Vanadium metallicum belongs to metal group with a atomic weight of 5.1

it is derived from vanadis a goddess of scandenvian mythology.it is obtained from the iron

ores of Sweden,it is analogous to chromium. [17]

Absorption and Distribution of Vanadium

A significant amount of vanadium absorption occurs in the upper gastrointestinal tract.

Most ingested vanadium probably is transformed to VO2+ in the stomach and passes into the

duodenum in this form

In serum, absorbed vanadium is transported mainly bound to transferrin [22]

Its action is that of an oxygen carrier and catalyzer, increases the amount

of hemoglobin .also increases and stimulates the phagocytes [18] .

Anemia, Emaciation. A remedy for degenerative conditions of liver

and arteries. acts as a tonic for digestivc functions.,

Addison’s disease, Atheroma fatty degeneration, innutrition [19]

In general, the toxicity of vanadium compounds is low.

Pentavalent compounds are the most toxic and the toxicity of vanadium compounds

usually increases as the valence increases. Most of the toxic effects of vanadium compounds

result from local irritation of the eyes and upper respiratory tract rather

than systemic toxicity [20] .

Experiments on animals ; the general action on animal system when injected into the veins

or alimentary canal ,is paralysis of motion ,convulsion ,local or general ,rapidly

supervening drowsiness or indifference to external circumstances congestion of

alimentary canal. Drowsiness and feebleness of pulse, [21]

研究设计

研究类型
Interventional
分配方式
Na
盲法
None

入排标准

年龄范围
15.00 Year(s) 至 49.00 Year(s)(—)
性别
Female

入选标准

  • Iron Deficiency Anaemia Patients with Hb % between 8 to 11 gms/dL.

排除标准

  • Severe Anaemia Patients with Hb % Less than 7 gms/dL
  • Females with Menorrhagia
  • Pregnancy and lactation 4.

结局指标

主要结局

1. Increase in Blood Hb Concentration

时间窗: 4 Months

2. Increse in Serum Ferritin Levels

时间窗: 4 Months

次要结局

  • Blood Haemogram - MCV and MCHC improvement(4 Months)

研究者

发起方
Vinayaka Missions Homoeopathic Medical College and Hospital
申办方类型
Private medical college
责任方
Principal Investigator
主要研究者

Nandhini R

Vinayaka missions Homoeopathic Medical college and hospital

研究点 (1)

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