NCT00716001
Unknown
Phase 4
Effect of Hydration With Sodium Bicarbonate for Long-Term Clinical Outcomes in Patients With Chronic Kidney Disease Undergoing an Emergent Coronary Procedure
Overview
- Phase
- Phase 4
- Intervention
- N-acetylcysteine
- Conditions
- Chronic Renal Failure
- Sponsor
- Osaka General Medical Center
- Last Updated
- 17 years ago
Overview
Brief Summary
This study is to evaluate the efficacy of sodium bicarbonate plus N-acetylcysteine for the prevention of contrast-induced nephropathy.
Investigators
Eligibility Criteria
Inclusion Criteria
- •patients with chronic renal failure(serum creatinine \>1.1mg/dl) undergoing elective percutaneous coronary intervention
Exclusion Criteria
- •administered with sodium bicarbonate and/or N-acetylcysteine and/or contrast media within 72 hours.
- •pregnancy
- •congestive heart failure
- •allergy to sodium bicarbonate and/or N-acetylcysteine
- •hemodialysis
Arms & Interventions
NAC
Intervention: N-acetylcysteine
nonNAC
Intervention: N-acetylcysteine
Outcomes
Primary Outcomes
Not specified
Similar Trials
Completed
Phase 3
Sodium Bicarbonate for Prevention of Contrast-Induced NephropathyRenal FailureNCT01172353Hospital Sao Lucas da PUCRS301
Completed
Not Applicable
Evaluation of the Effects of Bicarbonate-calcium Water in Premenopausal and Postmenopausal Women as a Prevention of OsteoporosisOsteoporosis RiskNCT05854342University of Salerno120
Terminated
Not Applicable
The Use of Sodium Bicarbonate in the Prevention of Contrast Induced NephropathyContrast Induced NephropathyNCT00494637Lenox Hill Hospital468
Completed
Not Applicable
Prevention of Contrast Nephropathy by Sodium Bicarbonate Versus Sodium Chloride and N-acetylcysteineAcute Renal Failure Contrast NephropathyNCT00353340Shaare Zedek Medical Center250
Unknown
Not Applicable
Effectiveness of Sodium Bicarbonate Buffered Anaesthetic Solution on Pain During InjectionLocal AnesthesiaNCT05473819Alexandria University27