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临床试验/NCT07490977
NCT07490977尚未招募不适用

Cross-Education of Combined Unilateral Strength and Balance Training on Motor Function in Older Adults With Bilateral Knee Osteoarthritis

University of Zagreb1 个研究点 分布在 1 个国家目标入组 45 人开始时间: 2026年9月1日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
45
试验地点
1
主要终点
Change from baseline in balance performance in older adults with bilateral knee osteoarthritis after 8 weeks of unilateral strength and/or balance training across all three intervention groups

研究概览

简要总结

Kinesitherapy is one of the main tools in the rehabilitation of knee osteoarthritis, but is often limited due to pain, reduced functionality, and fear of falling in older adults. This study will, through three sub-studies, examine the effects of unilateral training programs on strength, movement control, balance, and pain in the contralateral leg, as well as on functionality, fall risk, and kinesiophobia in older adults with bilateral knee osteoarthritis through three sub-studies. A total of 45 participants (aged 60-80 years) with bilateral knee osteoarthritis will be randomly assigned to one of three groups: 1. combined unilateral strength and balance training; 2. unilateral balance training; 3. unilateral strength training. Strength will be measured with maximal voluntary contraction, balance using a single leg stance test on an unstable surface, movement control with an active joint position reproduction test, and functionality using the six-minute walk test and the Western Ontario and McMaster Osteoarthritis Index questionnaire. Pain will be assessed with the Visual Analog Scale and the Intermittent and Constant Osteoarthritis Pain questionnaire, fall risk with the Timed Up and Go test and the Falls Efficacy Scale-International questionnaire, and kinesiophobia using the TAMPA questionnaire. This study will expand knowledge on cross-transfer and its effects on symptoms in the rehabilitation of older adults with bilateral knee osteoarthritis.

This research is a part of a doctoral thesis conducted under the supervision of assoc. prof. Tatjana Trošt, PhD.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
None

入排标准

年龄范围
60 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • age 60-80 years,
  • bilateral knee osteoarthritis of grade II-III according to the Kellgren-Lawrence classification

排除标准

  • acute lower extremity injuries in the past year,
  • taking nonsteroidal anti-inflammatory drugs within the past month,
  • involvement in physical therapy within the past 6 months,
  • undergoing intra-articular injections and/or knee surgery within the past year,
  • rheumatoid arthritis, septic arthritis, uncontrolled diabetes, other systemic inflammatory and autoimmune diseases, and severe cardiovascular, renal, and hepatic comorbidities

结局指标

主要结局

Change from baseline in balance performance in older adults with bilateral knee osteoarthritis after 8 weeks of unilateral strength and/or balance training across all three intervention groups

时间窗: From baseline (pre-intervention) to the end of the 8-week training program

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Lara Juriša

PhD Candidate

University of Zagreb

研究点 (1)

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