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Comparison of Different Weight Loss Methods in Obese Individuals

Not Applicable
Conditions
Obesity
Interventions
Behavioral: EXERCISE
Device: AURICULAR VAGUS NERVE STIMULATION
Behavioral: DIET
Registration Number
NCT05511376
Lead Sponsor
Bahçeşehir University
Brief Summary

Although obesity is a rapidly increasing epidemic worldwide, it is associated with many health-related comorbidities. As a result of the developments in social life and observes the sedentary life in individuals, an effect of the age of technology the fact that this epidemic will cause even massive health problems in the coming period affecting the health systems of countries and indirectly their economies that, This situation necessitates the creation of alternative treatment methods for the prevention of obesity. This study aims to determine the effect of a therapy approach that can be applied to the vagus nervous system, which is associated with many organs and systems, on weight loss and general health. As an alternative treatment against lifestyle changes such as diet and exercise, individuals have made for weight loss.

Detailed Description

Not available

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
90
Inclusion Criteria
  • Age range 18 - 65
  • Being in the stage I, II and III obesity class
Exclusion Criteria
  • Those with unstable DM
  • Those with stage II hypertension
  • Those who have had cardiovascular disease (especially those who have had an attack)
  • Those with pulmonary disease
  • Those with kidney disease
  • Orthopedic restrictions
  • Those with MND
  • Those tied to the chair

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
EXERCISEEXERCISEA pre-exercise breathing exercise study was planned. Exercise: It was planned to apply the Moderate Resistant Exercise Protocol (3 days a week for 60 minutes) and as aerobic exercise, walking 5 days a week (150 minutes / week) as 30 minutes / day.
AURICULAR VAGUS NERVE STIMULATIONAURICULAR VAGUS NERVE STIMULATIONThe Vagustim device was applied in Biphasic, Frequency 10 Hz, Modulation mode, with a pulse width of 300 μs, for 30 minutes /3 days/week by keeping the current intensity constant where the participants felt comfortable. It will be applied as bilateral VSS from the tragus and turbinate parts of the ear.
DIETDIETPersonal nutrition programs were prepared according to ideal body weight, with protein intake as 30% of total daily calories or 1-1.2 g/kg.
Primary Outcome Measures
NameTimeMethod
Biophysical Methods4th week

It includes The Timed Up and Go Test (sec). ( It show the temporal variation values in performing a certain activity. Functional activity and used to assess balance. Completion of test activity in a short time indicates positive development.)

6-Min Walk Test4th week

The 6-minute walk test includes value O2 saturation (mmHg). (Increased O2 saturation indicates that functional values develop positively.)

Handgrip strength test4th week

The Handgrip strength test (kg) measurement evaluates muscle strength.

Body Analysis4th week

BIA measurement include (internal adiposity).

Anthropometric Measurements4th week

It includes waist-hip ratio measurements.

Biochemical parameters4th week

It includes HDL (mg/dL), LDL (mg/dL), TG (mg/dL), and Total cholesterol (mg/dL) values.

Secondary Outcome Measures
NameTimeMethod
Quality of Life Questionnaire (Short Form - SF-36)Study start, 2nd & 4th week

It was used to evaluate the effect of weight on quality of life. (It is evaluated in the range of 0 - 100 points. Energy/vitality, physical function, mental health, general health perception, social functionality scores show a positive development as they approach the maximum value. Physical role difficulty, emotional role difficulty and Pain scores show a positive development as they approach the minimum value.)

International Physical Activity Questionnaire (Short Form- IPAQ)Study start, 2nd & 4th week

It has been used to examine physical activity levels. (Weekly physical activity levels are measured by MET value calculations. An increase in MET values indicates an increase in activity.)

Food Cravings Questionnaire (FCQ)Study start & 4th week

It was used to determine the cravings for foods. (In the scale, a scoring system between 39-234 points is used for sub-dimensions.It shows that there is a positive development as the scale approaches the minimum result.)

Visual Analog Scale (VAS)Study start, 2nd & 4th week

It was used to determine the cravings for foods. (A scoring system from 0 to 10 is used.It shows that there is a positive development as the scale approaches the minimum result.)

Trial Locations

Locations (1)

Avicenna Hospital

🇹🇷

Istanbul, Turkey

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