Comparative Genomic and Genetic Analysis of Paired Primary Breast - Metastatic Tumor Specimens Using High-throughput Platforms
- Conditions
- Breast Cancer
- Registration Number
- NCT01227733
- Lead Sponsor
- National University Hospital, Singapore
- Brief Summary
Adequate quality and quantity of RNA may be extracted from paraffin-embedded tumor blocks for gene expression analysis. This has clinical relevance as gene expression signatures may then be profiled using archival tumor blocks, which are more readily available than frozen tissues.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- Female
- Target Recruitment
- Not specified
Inclusion Criteria
No participants are involved.
Exclusion Criteria
No participants are involved.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms drive metastasis in breast cancer as identified by NCT01227733 genomic analysis?
How do gene expression signatures from paraffin-embedded tumors compare to frozen tissues in predicting breast cancer outcomes?
What biomarkers for patient selection were validated in NCT01227733's comparative genomic study of breast cancer subtypes?
What adverse events are associated with high-throughput genomic analysis in metastatic breast cancer research?
How does NCT01227733's RNA extraction method impact the identification of therapeutic targets in archival breast tumor samples?
Trial Locations
- Locations (1)
National University Hospital
🇸🇬Singapore, Singapore
National University Hospital🇸🇬Singapore, Singapore