Comparison of Corneal High Order Aberrations After Stream Light Trans-PRK and Mechanical Photorefractive Keratectomy
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Corneal high order aberrations measured before and after the intervention by corneal topography machine
研究概览
简要总结
Compare corneal high order aberrations before and after stream light trans-PRK and mechanical photorefractive keratectomy including third order aberrations; Trefoil and coma aberrations and forth order aberrations; spherical aberrations
详细描述
Laser technology has played an important role in promoting the development of ophthalmology, especially corneal refractive surgery.1 Trans-epithelial photorefractive keratectomy (Trans-PRK) has become a highly researched topic in recent years.2 Different epithelial debridement methods with PRK showed favorable results for the surgical treatment of low to moderate myopia3. In mechanical PRK (m-PRK), epithelial debridement is achieved using a blunt spatula, whereas in stream light trans-PRK (t-PRK), there after an excimer laser is used to ablate corneal stroma3. The Stream Light t-PRK is a safe and effective treatment option for the correction of low to moderate myopia.4 Many studies have shown that the corneal asphericity developed significantly after refractive surgeries and introduce higher-order aberrations (HOAs).2 The present study focused on three of the most clinically important HOAs; spherical, coma, and trefoil aberrations, both preoperative and postoperative were recorded from topography over the 6-mm-diameter central corneal zone using Pentacam.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 40 Years(Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •• Stable refraction for 1 year (refraction does not exceed 1D more than the last prescribed glasses).
- •Discontinuation of soft contact lens wears at least 1 week before examination.
- •Topography criteria:
- •Corneal thickness equal or more than 470 um
- •Symmetrical bow-tie
- •Back elevation not more than +12
- •Normal Belin\Ambrosio Enhanced ectasia display
- •Spherical equivalent not more than -6D.
排除标准
- •• Previous ocular surgery
- •Concurrent ocular pathology; corneal scar, corneal dystrophy
- •Systemic disease; Uncontrolled diabetes, collagen disease
- •Post-operative complications; sub-epithelial haze.
结局指标
主要结局
Corneal high order aberrations measured before and after the intervention by corneal topography machine
时间窗: 1 monthe after surgery
* Third order aberrations; Trefoil and coma aberrations * Forth order aberrations; spherical aberrations Trefoil, spherical and coma aberrations
次要结局
未报告次要终点
研究者
Khaled Abdelazeem
Associate professor
Assiut University
