Efficiency of slow loaded breathing training on cardiovascular functions in COPD with hypertensio

Phase 2

• Conditions: Chronic obstructive pulmonary diseasehigh blood pressurehypertensionSlow brathing trianingSlow loaded breathing training; Chronic obstructive pulmonary disease; high blood pressure; hypertension; Slow brathing trianing; Slow loaded breathing training

• Registration Number: TCTR20180530007
• Lead Sponsor: /A

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2018-05-30
• Study Completion: 2018-12-01
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending (Not yet recruiting)
• Sex: All
• Target Recruitment: 34

Inclusion Criteria

1. COPD patients stage I-IV with hypertension
2. Good communication and cooperation
3. Good cognition with MMSE†Thai 2002 (Mini †Mental State Examination: Thai version) score more than 17 points with full scores are 30 points.
4. Stable COPD without acute exacerbation in the previous 4 weeks
5. Independent physical activity
6. Arm and hand can performed isometric handgrip exercise.

Exclusion Criteria

1. Medical history related with contraindication of exercise including significant resting ECG suggesting ischemia, recent myocardial infarction, or cardiac event, unstable angina, uncontrolled dysrhythmias with symptoms or hemodynamic compromise and symptomatic heart failure, symptomatic severe aortic stenosis, acute myocarditis or pericarditis, and suspected or known dissecting aneurysm.
2. Using oxygen therapy.
3. History of renal disease or renal dysfunction, neuromuscular disease: cerebrovascular accident, spinal cord injuries.
4. Medical history of pneumothorax, recent lung surgery (within 12 months), and spontaneous rib fractures.
5. Pulmonary hypertension or pulmonary edema which unrelated with COPD, pulmonary infection, pneumonitis, pulmonary fibrosis with symptoms, active lung tuberculosis, and interstitial lung disease with symptom.
6. Musculoskeletal disorders including; severe osteoporosis, limit shoulder flexion ≤ 90o, hand function impairment.
7. Secondary hypertension
8. Visual impairment, hearing impairment.
9. Pulse oxygen saturation less than 90% at resting
10. Current smoking
11. Current another exercise training program which effect to results of this study.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
mornig home blood pressure and heart rate pre-trianing, post-trianing and after sustain period Digital blood pressure and heart rate monitoing

Secondary Outcome Measures

Name	Time	Method
Automonic nervous system activities on cardiovascular pre-trianing, post-trianing and after sustain period Heart rate variability and blood pressure variability,Arterial stiffness pre-trianing, post-trianing and after sustain period finger-toe pulse wave velocity,Baroreflex sensitivity pre-trianing, post-trianing and after sustain period Valsalva maneuver