Phosphatase & tensin homolog (PTEN) is a tumor supressor gene used in this study as immunohistochemistry marker for detecting loss of PTEN in Atypical Endometrial Hyperplasia and Endometrioid Endometrial Carcinoma
Not Applicable
- Conditions
- Health Condition 1: C541- Malignant neoplasm of endometrium
- Registration Number
- CTRI/2023/06/053964
- Lead Sponsor
- Jawaharlal Nehru Medical College, Sawangi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Cases diagnosed on biopsy or surgical specimen of endometrial carcinoma and hyperplasia with correlating clinicopathological features
Exclusion Criteria
Endometrial biopsy with inflammatory histomorphology, deficient clinical data and endometrium without representative histomorphology of precancerous and cancerous lesion
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Immunohistochemical evaluation of PTEN expression is likely to be useful in screening precancerous hyperplasia lesions & detecting earliest stage of endometrial carcinoma.Timepoint: 2 years
- Secondary Outcome Measures
Name Time Method To assess whether PTEN is a feasible marker or not.Timepoint: 2 years