Impact of Fish Oil Supplementation in 3rd Trimester of Pregnancy on Maternal and Offspring Health
- Conditions
- Preterm DeliveryAtopyMetabolic Syndrome
- Interventions
- Dietary Supplement: Fish oilDietary Supplement: Olive oil
- Registration Number
- NCT01353807
- Lead Sponsor
- Centre for Fetal Programming, Denmark
- Brief Summary
The aim of the trial is to investigate the effect of daily supplementation with 2.7 grams of long chain n-3 fatty acids during the third trimester of pregnancy. In 1990, 533 pregnant women, while they were in gestational week 30, were randomized to fish oil supplements providing the mentioned amount of long chain n-3 fatty acids, olive oil supplements, or no supplements; they were asked to take the supplements until delivery. Health outcomes were assessed during pregnancy and delivery. Further, offspring health and development has been examined during the ensuring two decades by making linkages to the rich Danish health and administrative registries, by asking the offspring to complete web-based questionnaires, and by examining the offspring physically.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 533
- Healthy pregnant women in gestation week 30
- Bleeding episodes during pregnancy
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Fish oil supplementation Fish oil These women received 4 1-g capsules of fish oil per day providing 2,7 grams long chain n-3 fatty acids per day, from gestation week 30 until delivery Olive oil Olive oil These women received 4 1-g capsules with olive oil per day from gestational week 30 until delivery
- Primary Outcome Measures
Name Time Method Gestation length 1989-1990 (1 year) We assesed impact of fish oil supplementation in pregnancy on timing of spontaneous delivery
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Aarhus University Hospital
🇩🇰Aarhus, Denmark