Impact of Fish Oil Supplementation in 3rd Trimester of Pregnancy on Maternal and Offspring Health

Not Applicable

Completed

• Conditions: Preterm Delivery; Atopy; Metabolic Syndrome

• Registration Number: NCT01353807
• Lead Sponsor: Centre for Fetal Programming, Denmark

Brief Summary

The aim of the trial is to investigate the effect of daily supplementation with 2.7 grams of long chain n-3 fatty acids during the third trimester of pregnancy. In 1990, 533 pregnant women, while they were in gestational week 30, were randomized to fish oil supplements providing the mentioned amount of long chain n-3 fatty acids, olive oil supplements, or no supplements; they were asked to take the supplements until delivery. Health outcomes were assessed during pregnancy and delivery. Further, offspring health and development has been examined during the ensuring two decades by making linkages to the rich Danish health and administrative registries, by asking the offspring to complete web-based questionnaires, and by examining the offspring physically.

Detailed Description

Not available

Study Timeline

• Primary Completion: 1990-12
• Study First Submitted: 2011-04-29
• Study Completion: 2011-05
• Study First Submitted QC: 2011-05-13
• Study First Posted: 2011-05-16
• Status Verified: 2014-02
• Last Update Submitted: 2014-02-27
• Last Update Posted: 2014-02-28

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 533

Inclusion Criteria

• Healthy pregnant women in gestation week 30

Exclusion Criteria

• Bleeding episodes during pregnancy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Gestation length	1989-1990 (1 year)	We assesed impact of fish oil supplementation in pregnancy on timing of spontaneous delivery

Trial Locations

Locations (1)

Aarhus University Hospital; 🇩🇰 Aarhus, Denmark