Gene expression of renin-angiotensin-system components in human leukocytes study
Not Applicable
- Conditions
- Patients with chronic kidney disease, hypertension, diabetes mellitus, dyslipidemia, obesity and healthy volunteer.
- Registration Number
- JPRN-UMIN000016846
- Lead Sponsor
- Department of Medical Science and Cardiorenal Medicine, Yokohama City University Graduate School of Medicine
- Brief Summary
We have obteined blood sample from 86 outpatients and 23 healthy volunteer. The leukocyte expression of ATRAP was positively correlated with the leukocyte count, serum CRP and leukocyte imflammatory cytokine expression in these outpatients.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 86
Inclusion Criteria
Not provided
Exclusion Criteria
Patinets i)who were 19 years-old or younger, ii)having corticosteroids or immunosuppressive medications within 3 month, iii)with hematological disorder, iv)with active infection, and v)that physician judged to be inappropriate.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The prevalence of non-communicating disease, including chronic kidney disease, hypertension, diabetes mellitus, and obesity.
- Secondary Outcome Measures
Name Time Method The progression to the end-stage renal disease, 50% reduction in eGFR, and all-cause mortality.