Vascular Inflammation Stratified by Body Size Phenotype
Completed
- Conditions
- ObesityMetabolic SyndromeAtherosclerosis
- Registration Number
- NCT01979068
- Lead Sponsor
- Korea University
- Brief Summary
* Vascular Inflammation is a key factor in both the pathogenesis and outcome of atherosclerosis. 18FDG-PET is a promising novel tool for identifying and quantifying vascular inflammation within atherosclerotic plaque
* Recently, unique subsets of obese individuals, such as metabolically obese but normal weight (MONW) and metabolically healthy obese (MHO), have been getting an attention
* Therefore, the purpose of this study is to examine the relationship of vascular inflammation,measured by FDG-PET, with various body sized phenotypes
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 250
Inclusion Criteria
- Healthy patients for visiting routine medical check in our clinic
Exclusion Criteria
- history of CVD (myocardial infarction, unstable angina, stroke, or cardiovascular revascularization)
- stage 2 hypertension (resting blood pressure, ≥160/100 mmHg)
- history of inflammatory conditions that affect the study results
- taking medications that might affect inflammatory status, including steroid and non-steroidal anti-inflammatory drug within 6 months
- or malignancy or severe renal or hepatic disease
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method max TBR values stratified by the four body size phenotypes 12 weeks
- Secondary Outcome Measures
Name Time Method Framingham risk scores according to the four body size phenotypes 12 weeks
Trial Locations
- Locations (1)
Korea University Guro Hospital
🇰🇷Seoul, Korea, Republic of