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Clinical Trials/CTRI/2020/07/026845
CTRI/2020/07/026845
Not yet recruiting
未知

Metabolic and Clinical Effect of Enteral Nutrition Therapy: Measured versus Estimated Energy Requirements in Critically ill Cirrhotic â?? A Randomized Controlled Trial - METALIC study

ICMR0 sites0 target enrollmentTBD

Overview

Phase
未知
Intervention
Not specified
Conditions
Health Condition 1: K721- Chronic hepatic failure
Sponsor
ICMR
Status
Not yet recruiting
Last Updated
4 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
4 years ago
Study Type
Interventional

Investigators

Sponsor
ICMR

Eligibility Criteria

Inclusion Criteria

  • 1\.Eligible for enteral feeding with a functional gastrointestinal tract (with or without SPN)
  • 2\.Mechanically ventilated patients expected to be on ventilator support for at least 5 days
  • 3\.Expected length of ICU stay greater than 3 days
  • 4\.Initiated on nutrition support (parenteral/or enteral nutrition)
  • 5\.The diagnosis documented by physician within one day of ICU admit
  • 6\. Signed informed consent

Exclusion Criteria

  • 1\.Active upper gastrointestinal bleeding
  • 2\.If there are conditions which precluded IC, such as an FiO2 \>60 %, failure to cooperate, agitation, seizure activity, spasticity, or positive end\-expiratory pressure (PEEP) \>10 mmHg.
  • 3\. Pregnant women
  • 4\. Refused to consent/ inability to obtain informed consent
  • 5\.Known long standing diabetic
  • 6\. If there is any evidence of medical/surgical instability
  • 7\. Hepatocellular carcinoma Extrahepatic malignancies
  • 8\. Those receiving total parenteral (TPN)
  • 9\. With persistent gastrointestinal dysfunction and ileus
  • 10\. Readmitted to the ICU

Outcomes

Primary Outcomes

Not specified

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