Does rotation of nasal interfaces decreases the incidence of nasal injury in neonates on nasal CPAP
- Conditions
- Health Condition 1: P073- Preterm [premature] newborn [other]
- Registration Number
- CTRI/2019/01/017320
- Lead Sponsor
- AIIMS Jodhpur
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1.Inborn preterm neonates of <35 weeks of gestation with respiratory distress requiring CPAP within first 6 hours of life. Respiratory distress has been defined as the presence of any two out of the three findings: tachypnea defined as a respiratory rate greater than 60/ min, retractions, expiratory grunt).
2.Neonates intubated in the delivery room for asphyxia or for surfactant administration and extubated to CPAP within 6 hours of life will be also eligible.
3.Inborn/outborn preterm neonates <35 weeks of gestation requiring CPAP/ NIMV as post-extubation respiratory support.
1.Perinatal asphyxia (5 minute Apgar score of <=3)
2.Life threatening congenital malformations such as congenital diaphragmatic hernia, trachea-esophageal fistula
3.Malformations that would prevent establishing CPAP such as Pierre-Robinson syndrome, choanal atresia, cleft lip and palate
4.Major congenital abnormality including antenatally diagnosed chromosomal abnormalities
5.Conditions where CPAP would be contraindicated such as
•Poor spontaneous respiratory efforts or apnea
•Worsening shock
•Suspected or proven PPHN
•Severe metabolic acidosis (pH <7.2 with base deficit > -10),
•Severe respiratory acidosis (pH <7.2 with PaCO2 >55mmHg)
•Massive pulmonary hemorrhage
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method