The Cartilage and Muscle Thickness on Knee Pain in Patients With Rheumatoid Arthritis

Completed

• Conditions: Knee Pain Chronic; Rheumatoid Arthritis; Cartilage Degeneration; Muscle Loss

• Registration Number: NCT05999266
• Lead Sponsor: Sisli Hamidiye Etfal Training and Research Hospital

Brief Summary

The knee pain status of the patients who are followed in the rheumatology special branch of the Physical Medicine and Rehabilitation Outpatient Clinic and who meet the inclusion criteria will be questioned. In patients with or without knee pain, the cartilage thickness measurement of the knee joint will be measured from 3 points by ultrasound. At the same time, Quadriceps and Hamstring muscle thickness measurements of the patients will be made from the midpoints where the muscle thickness is the highest. The physician who performed the ultrasonographic measurements of the knee pain status of the patients does not know.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2023-08-13
• Study First Submitted QC: 2023-08-13
• Study First Posted: 2023-08-21
• Study Start: 2023-09-28
• Status Verified: 2023-11
• Primary Completion: 2023-11-10
• Study Completion: 2023-11-12
• Last Update Submitted: 2023-11-20
• Last Update Posted: 2023-11-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 130

Inclusion Criteria

• Rheumatoid Arthritis > Diagnosed for 1 year
• -Female gender
• -The patient has been in remission or low disease activity for at least 3 months
• -Be able to ambulatory
• -No significant deformity in the lower extremity joints

Exclusion Criteria

• Patient with active arthritis or high disease activity

  • • Significant deformity of the lower extremity joints and inability to ambulate
  • -Pregnant patient
  • • Presence of malignancy
  • • Patient with a severe psychiatric disorder and difficulty in cooperation
  • • Presence of cardiovascular and pulmonary comorbidities that will prevent exercise
  • -Male gender

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Ultrasonographic Cartilage Thickness Measurement	through study completion, an average of 1 month	Tibial cartilage thickness will be visualized by ultrasound with the knee held in 30 degrees of flexion, and 3 measurements will be taken from the medial, lateral and midline.
Ultrasonographic Muscle Measurement Thickness Measurement	through study completion, an average of 1 month	The quadriceps muscle thickness will be measured by determining the midpoint between the SIAS and the patella while the patient is lying in the supine position. Hamstring muscle thickness will be measured at the intersection of a line drawn at 60% distal between the greater trochanter and the outer femoral condyle, and at the midline of the popliteal fossa, with the patient lying on the prone. These 2 measurements will be proportional to each other.

Trial Locations

Locations (1)

University of Health Sciences, Şişli Hamidiye Etfal Training and Research Hospital; 🇹🇷 Istanbul, Turkey