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临床试验/NCT05218863
NCT05218863已完成不适用

Incidence, Diagnosis, Management and Outcome of Acute Mesenteric Ischaemia: a Prospective, Multicentre Observational Study

University of Tartu3 个研究点 分布在 2 个国家目标入组 709 人开始时间: 2022年6月6日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
709
试验地点
3
主要终点
Incidence of AMI

研究概览

简要总结

This is a prospective, multicentre observational study screening all adult patients admitted to a participating hospital over a 6-month study period (may be adjusted to 4-8 months according to recruitment) and including all patients with suspicion of or confirmed acute mesenteric ischaemia (AMI).

Only admission data and hospital mortality outcome will be collected for patients in whom suspicion of AMI is not confirmed. For patients with confirmed AMI full data collection regarding diagnostics, management and long-term outcome is required.

Investigators aim to recruit 40-50 sites with expected median of 10-20 patients with confirmed AMI per site during the study period (naturally depending on the size of the hospital). The start of the study is planned for Spring 2022.

The aim of the study is to identify the incidence of AMI and its different forms in adult hospitalized patients, and to describe patient characteristics (demographic, clinical and laboratory) at baseline, applied diagnostics and management, as well as outcomes in patients with AMI. An additional aim is to compare the baseline characteristics and outcomes of patients with confirmed AMI to those of patients with suspected AMI in whom the diagnosis was not confirmed.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • All patients with suspected AMI

排除标准

  • Age <18 years Consent declined by patient or next of kin Chronic mesenteric ischaemia without an acute event

结局指标

主要结局

Incidence of AMI

时间窗: 6 months

Incidence of AMI in hospitalized adult patients in acute care hospitals

次要结局

  • Proportion of different forms of AMI(6 months)
  • Time to diagnosis(through study completion, study duration 6 months)
  • 1 year survival(1 year)
  • Quality of life score(1 year)
  • 30 days survival of AMI(30 days after admission/suspicion of AMI/study inclusion)
  • Treatment(through study completion, study duration 6 months)
  • Time to treatment(through study completion, study duration 6 months)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Annika Reintam Blaser

A/Professor

University of Tartu

研究点 (3)

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