Incidence, Diagnosis, Management and Outcome of Acute Mesenteric Ischaemia: a Prospective, Multicentre Observational Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 709
- 试验地点
- 3
- 主要终点
- Incidence of AMI
研究概览
简要总结
This is a prospective, multicentre observational study screening all adult patients admitted to a participating hospital over a 6-month study period (may be adjusted to 4-8 months according to recruitment) and including all patients with suspicion of or confirmed acute mesenteric ischaemia (AMI).
Only admission data and hospital mortality outcome will be collected for patients in whom suspicion of AMI is not confirmed. For patients with confirmed AMI full data collection regarding diagnostics, management and long-term outcome is required.
Investigators aim to recruit 40-50 sites with expected median of 10-20 patients with confirmed AMI per site during the study period (naturally depending on the size of the hospital). The start of the study is planned for Spring 2022.
The aim of the study is to identify the incidence of AMI and its different forms in adult hospitalized patients, and to describe patient characteristics (demographic, clinical and laboratory) at baseline, applied diagnostics and management, as well as outcomes in patients with AMI. An additional aim is to compare the baseline characteristics and outcomes of patients with confirmed AMI to those of patients with suspected AMI in whom the diagnosis was not confirmed.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients with suspected AMI
排除标准
- •Age <18 years Consent declined by patient or next of kin Chronic mesenteric ischaemia without an acute event
结局指标
主要结局
Incidence of AMI
时间窗: 6 months
Incidence of AMI in hospitalized adult patients in acute care hospitals
次要结局
- Proportion of different forms of AMI(6 months)
- Time to diagnosis(through study completion, study duration 6 months)
- 1 year survival(1 year)
- Quality of life score(1 year)
- 30 days survival of AMI(30 days after admission/suspicion of AMI/study inclusion)
- Treatment(through study completion, study duration 6 months)
- Time to treatment(through study completion, study duration 6 months)
研究者
Annika Reintam Blaser
A/Professor
University of Tartu
