Effects of Physical Training on the heart and nervous system of patients attending a cardiac rehabilitation program

Not Applicable

Recruiting

• Conditions: Heart Defects, Congenital

• Registration Number: RBR-497mxmm
• Lead Sponsor: niversidade do Estado do Rio de Janeiro

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2023-01-12
• Last Update Posted: 29 May 2023
• Study Completion: 2024-01-01

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Be aged between 40-70 years. For the groups composed of people with cardiovascular impairment: be enrolled in the cardiac rehabilitation service of Hospital Universitário Pedro Hernesto (HUPE)

Exclusion Criteria

For groups composed of people with cardiovascular impairment: practice of regular physical exercises (= 3 days/week for 30 min) in the last 6 months; malnutrition; use of antidepressant medication; smoking habit. In addition to the aforementioned criteria, for healthy control subjects, those with a previous or current diagnosis of arterial hypertension; coronary artery disease; heart failure; ischemic disease; pulmonary disease; diabetes mellitus; Chagas disease; tuberculosis; and/or use of antihypertensive medication ill not be considered eligible

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Systolic and diastolic blood pressure will be measured in the non-dominant arm using a digital sphygmomanometer (Omron HEM - 7113, Kyoto, Japan) positioned around the proximal third of the arm. Data will be collected at rest and every minute during the cold pressure test and PECA. Autonomic modulation will be evaluated through heart rate variability (HRV), obtained by analyzing the RR intervals recorded by a heart rate monitor (Polar V800 XC, Kempele, FIN). The analysis of the data obtained for HRV was performed in the time and frequency domains, using the Kubios HRV program (Version 3.4, Kuopio, Finland). The time domain variables were: mean of RR intervals (RRi), standard deviation of NN intervals (SDNN), square root of successive mean squared differences of adjacent RRi (rMSSD) and percentage number of adjacent RRi pairs differing by more than 50 ms from the previous RRi (pNN50).