Effects of Spicy Diet on Salty Taste and Salt Intake
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 606
- 试验地点
- 1
- 主要终点
- Effects of spicy diet on salt taste
研究概览
简要总结
Excess dietary salt intake is closely associated with the development of hypertension and cardiocerebral vascular diseases. Reduction in high salt intake significantly prevents hypertension and cardiocerebral events. Currently, few promising method is available to reduce salt intake in human. This study focus on examining the salty taste in population-level and exploring whether dietary factors can reduce salt intake through acting on salty taste.
详细描述
Hypertension and its related complications are common health problems that can lead to multiple organ damage and death. Excessive salt intake plays very important role in the development of hypertension. Reducing salt intake prevents high blood pressure as well as cardiocerebral vascular diseases.
The experimental design is a multi-center, random-order, double-blind observational study to investigate the salty taste and salt intake in population-level.
A total of 606 individuals from four cities in China are recruited in this study. This study aims to explore the salty taste characterization and salt intake in participants who like or dislike spicy diet through questionnaire, spicy preference, salty perception and super-threshold as well as the 24-hour urinary sodium excretion.
研究设计
- 研究类型
- Observational
- 观察模型
- Ecologic Or Community
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age ≥ 18 years and ≤ 55 years.
- •Willing and able to provide written informed consent.
- •Willing and able to comply with all study procedures.
排除标准
- •Hypogeusia or loss due to neural system disease or oral and digestive disease.
- •Capsaicin allergy and poor compliance.
- •Recently oral diuretics and participate in other pharmacological experiment in 3 months.
- •Acute infection, cancer, serious arrhythmias, drug or alcohol abuse.
- •Currently have cold, fever, acidosis, dehydration, diarrhea, vomiting during the study.
- •Unwilling or unable to communication due to the dysnoesia and language disorders
- •Severe neural or psychiatric diseases that would preclude fully understand and corporation in the study.
- •Pregnancy or lactation
- •Unwilling to sign the informed consent
结局指标
主要结局
Effects of spicy diet on salt taste
时间窗: Day 1
Daily spicy food intake was evaluated by diet questionnaire and salty taste was tested through salt perception and super-threshold examination on the first day when the participant was investigated.
次要结局
- Effects of spicy diet on salt intake(Day 1)
- Effects of spicy diet on obesity parameters.(Day 1)
- Effects of spicy diet on blood pressure(Day 1)
研究者
Zhiming Zhu
Director of the Dept. of Hypertension & Endocrinology
Third Military Medical University