Characterisation of neuropsychological and motoric performance in patients with hyponatremia

• Conditions: E87.1; Hypo-osmolality and hyponatraemia

• Registration Number: DRKS00004278
• Lead Sponsor: niversität zu Köln

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2012-08-09
• Results First Posted: 2020-03-04
• Study Completion: 2022-04-30
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 176

Inclusion Criteria

1. Men and women of 18 years of age or older
2. Hyponatremia with serum sodium < 130 mmol/l

Exclusion Criteria

1. traumatic cerebral injury, hemorrhagic and ischemic insult as cause of hyponatremia
2. professional or private relationship between subject and the investigators or dependance on the investigators
3. Placement in an institution based on official orders
4. Patients who are incapable of giving informed consent

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Patients score in the following neuropsychological and motoric tests during phase of hyponatremia (< 130 mmol/l) and after at least 48 hours. Dem-Tect- signs of dementia; MMST- cognitive deficits; Trail-Making-Test- psychomotoric speed and executive functions; BDI-V- signs of depression; Timed-up and go- motoric deficits.

Secondary Outcome Measures

Name	Time	Method
Quality of life SF-36<br>during phase of hyponatremia (< 130 mmol/l) and after increase of serum sodium > 10 mmol/l or normalization of serum sodium level after at least 48 hours