Transfusion induced complications = transfusion associated complications? study
Completed
- Conditions
- Blood transfusions complicationsSigns and SymptomsBlood transfusions
- Registration Number
- ISRCTN48093674
- Lead Sponsor
- eiden University Medical Centre (LUMC) (Netherlands)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 1548
Inclusion Criteria
Acute aneurysm-, elective aneurysm-, orthopaedic- and large gastro-intestinal surgery patients.
Exclusion Criteria
1. Under 18 years of age
2. Transfusions received within 3 months prior to inclusion
3. Pre existing medical indication for filtered red blood cell transfusions
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Postoperative:<br>1. In-hospital mortality<br>2. Duration of intensive care stay
- Secondary Outcome Measures
Name Time Method 1. Postoperative multi organ failure<br>2. Postoperative infections<br>3. Length of hospital stay<br>4. Costs/benefits of universal leukocyte depletion for the Dutch health care<br>5. Role of perioperative medication<br><br>Follow up :<br>1. Long term survival<br>2. Cancer recurrence in GI patients<br>3. Predictive role of cytokines and related genes