Transvaginal Ultrasonography Guided Embryo Transfer

Not Applicable

Completed

• Conditions: Infertility, Female
• Interventions: Procedure: transvaginal ultrasound guided embryo transfer; Procedure: transabdominal ultrasound guided embryo transfer

• Registration Number: NCT03473028
• Lead Sponsor: Kasr El Aini Hospital

Brief Summary

to evaluate the value of using transvaginal ultrasound guided embryo transfer in obese patients undergoing in vitro fertilization.

Detailed Description

The 800 participants with body mass index more than 30kg/m2 were randomly allocated to two groups of equal size using an automated web-based randomization system. The first group 400 patient undergoing the transabdominal-guided embryo transfer, the second group 400 patient undergoing transvaginal-guided embryo transfer.

Study Timeline

• Study First Submitted: 2018-03-15
• Study First Submitted QC: 2018-03-20
• Study First Posted: 2018-03-21
• Study Start: 2018-04-01
• Primary Completion: 2021-02-18
• Study Completion: 2021-03-04
• Status Verified: 2021-04
• Last Update Submitted: 2021-04-06
• Last Update Posted: 2021-04-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 800

Inclusion Criteria

• BMI more than 35, good ovarian reserve, unexplained infertility more than 3 years.

Exclusion Criteria

• severe male factor of infertility,uterine factor of infertility excluded by ultrasonography and hysteroscopy ,ovarian endometrioma or patients with poly cystic ovary syndrome, obesity caused by abnormal endocrine function (thyroid or adrenal disorder)

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
transvaginal group	transvaginal ultrasound guided embryo transfer	400 obese female undergo transvaginal ultrasound guided embryo transfer
transabdominal ultrasound	transabdominal ultrasound guided embryo transfer	400 obese female undergo transabdominal ultrasound guided embryo transfer

Primary Outcome Measures

Name	Time	Method
clinical pregnancy rate'	4 weeks following embryo transfer	the presence of at least one intrauterine gestational sac with viable fetus.

Secondary Outcome Measures

Name	Time	Method
live birth rate	immediately following delivery	delivery of a living baby

Trial Locations

Locations (1)

Kasr El Ainiy Hospital; 🇪🇬 Cairo, Egypt