Comparison of two drugs,dexmedetomidine and midazolam for sedation during awake fiberoptic intubatio
Not Applicable
- Conditions
- Health Condition 1: C00-C14- Malignant neoplasms of lip, oral cavity and pharynx
- Registration Number
- CTRI/2019/08/020698
- Lead Sponsor
- Department of AnaesthesiologySMS Medical collegeJaipur
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients undergoing oral cancer
surgeries requiring nasal intubation.
Patients willing to give written informed
consent.
Patients of either sex
ASA Grade II & III
Age Groups-18-60 years
Weighing 40 to 70 kg â?? BMI < 40kg/m2
Exclusion Criteria
Patient refusal.
Known or admitted alcohol or drug abusers.
Allergic to the drugs involved in the study.
Bleeding disorders.
Existing cardiovascular diseases.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To determine the difference in patient comfort score during intubation in both the groups.Timepoint: Comfort Scale values will be recorded during preoxygenation (Pre-Ox), at introduction of fiberoptic scope (time point designated as FOS), and at introduction of the endotracheal tube (time point designated as ET).
- Secondary Outcome Measures
Name Time Method 1.To determine the difference in hemodynamic variables(HR,SBP,DBP,SpO2) at different time intervals in both the groups. <br/ ><br>2.To determine the difference in patients tolerance during intubation in both the groups. <br/ ><br>3.To determine the difference in patient satisfaction in both the groups. <br/ ><br>4.To find out adverse reactions to the drugs if any. <br/ ><br> <br/ ><br>Timepoint: Heart rate,systolicBP, and diastolicBP,SpO2 will be recorded at the end of loading dose of study drug and then at 1 minute intervals until the placement of endotracheal tube and 1 minute and 3 minute after intubation.One study blinded observer will assess patientâ??s reaction to placement of the fiberoptic scope and the endotracheal tube on a scale of 1 to 5.24 hours after the surgical procedure, each patient will be questioned to assess his/her experience with the AFOI.