The effect of N-acetylcysteine (NAC) in patients with moderate traumatic brain injury (MTBI)
Phase 3
Recruiting
- Conditions
- Traumatic brain injury.Traumatic cerebral oedema
- Registration Number
- IRCT2017010131709N1
- Lead Sponsor
- Vice Chancellor for research of Arak University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 104
Inclusion Criteria
Patients older than 18 years old.; patients with moderate traumatic brain injury; The GCS between 9 and 13; Filling out the informed consent form by the patient or the accompanies.
Exclusion criteria:
Unwillingness to participate in the study; Patients who have consumed alcohol or used narcotics at anytime while diagnosed with MTBI; Patients who showed an allergic reaction to NAC
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Superoxide dismutase. Timepoint: Before treatment, six hours after the first dose. Method of measurement: Blood samples will be taken from patients and initial values of blood antioxidant enzymes: (Superoxide dismutase U/ml ) will be recorded in the checklist.;Glutathione peroxidase. Timepoint: Before treatment, six hours after the first dose. Method of measurement: Blood samples will be taken from patients and initial values of blood antioxidant enzymes: (Glutathione peroxidase U/l ) will be recorded in the checklist.
- Secondary Outcome Measures
Name Time Method