Rehabilitation of Acute Hamstring Injuries in Male Athletes

Not Applicable

Completed

• Conditions: Strains
• Interventions: Other: Physiotherapy ASPETAR; Other: Physiotherapy ASPETAR+

• Registration Number: NCT02104258
• Lead Sponsor: Aspetar

Brief Summary

The purpose of the study is to compare the effect of two rehabilitation protocols with different emphasis on eccentric exercises after acute hamstring muscle strain injuries on the time to return to sports (RTS) and the rate of re-injuries in male athletes.

The hypothesis is that the addition of early eccentric hamstring exercises being performed at longer muscle-tendon length towards end range of motion alter the outcomes RTS and re-injuries in a rehabilitation protocol after acute hamstring muscle strain injuries.

Detailed Description

Background and rationale:

Acute hamstring muscle strain injuries represent the most prevalent non-contact muscle injury reported in sports. Despite the high prevalence and a rapidly expanding body of literature investigating hamstring muscle strain injuries, \[1\] occurrence and re-injury rates have not improved over the last three decades \[2\]. Therefore, rehabilitation and secondary prevention are of particular concern, and the primary objective of all rehabilitation protocols is to return an athlete to pre-injury level as soon as possible with a minimal risk of injury recurrence.There is still a lack of consensus and clinical research regarding the effectiveness of various rehabilitation protocols for acute hamstring injuries in athletes participating in sports with high sprinting demands \[3,4\]. To our knowledge, there are no prospective, randomised trials investigating the effect of different rehabilitation protocols in a Middle-Eastern athletic population. Eccentric strength training has shown to reduce the risk of both new acute hamstring injuries as well as re-injuries \[5,6\], whereas hamstring exercises being performed at longer muscle-tendon length, preferentially mimicking movements occuring simultaneously at both the knee and hip are reported to be more effective than a protocol containing conventional exercises \[7\], and are suggested to be a key strategy in the management of hamstring injuries. However, the preventive effect related to the eccentric training remains unclear and is still debated and the optimal intensity of eccentric training in rehabilitation of acute hamstring strain injuries and prevention of re-injuries is yet unknown \[8\].

The primary objective in this study is therefore to compare the effect of two rehabilitation protocols after acute hamstring muscle strain injuries on the time to return to sports (RTS) and the rate of re-injuries in male athletes in a prospective single-site randomized controlled trial.

The investigators aim to include 90 male athletes with clinical signs and MRI abnormalities consistent with an acute hamstring muscle strain injury. The injured athletes will be randomised into one of two different rehabilitation protocols with unlike emphasis on eccentric exercises.

Study Timeline

• Study Start: 2014-03
• Study First Submitted: 2014-03-22
• Study First Submitted QC: 2014-04-02
• Study First Posted: 2014-04-04
• Primary Completion: 2019-02-20
• Status Verified: 2020-02
• Study Completion: 2020-02-20
• Last Update Submitted: 2020-02-24
• Last Update Posted: 2020-02-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 90

Inclusion Criteria

• Male athletes

• Age 18-50 years

• Acute onset posterior thigh pain when training or competing, identified as:

  1. Patient reported sudden event
  2. Patient reported pain in posterior thigh

• Clinical diagnosis of an acute hamstring muscle strain injury, defined as:

  1. Localised pain during palpation of hamstring muscle
  2. Increasing pain during isometric contraction
  3. Localised pain when performing a passive straight leg raise test

• MRI confirmed isolated hamstring lesion (increased high signal intensity on fat saturated sequences)

• MRI performed ≤5 days from injury

• Available for ≥3 physiotherapy sessions per week at Aspetar

• Available for follow-up

Exclusion Criteria

• Patients with verified or suspected previous hamstring injury within the last 6 months in the same leg
• Chronic hamstring complaints >2 months
• Grade III injury including complete hamstring disruption or avulsion of all tendons
• Contraindications to MRI
• Patients that do not have an intention to return to full sport activity
• Patients that do not want to receive one of the two therapies

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Physiotherapy ASPETAR	Physiotherapy ASPETAR	The patients will follow the ASPETAR Hamstring Rehabilitation Protocol, which is a standardised physiotherapy protocol, including range of motion exercises, progressive strengthening exercises, core stability training and agility exercises \[10\]. The ASPETAR protocol consist of predefined rehabilitation stages including sports specific stages. Specific functional based criteria for progression will be utilized for each of the six rehabilitation stages. No pain provocation when performing the exercises will be allowed. The rehabilitation will be initiated as soon as possible after inclusion and the patients will be supervised by experienced physiotherapists in the Rehabilitation Department at Aspetar 3 to 5 days per week.
Physiotherapy ASPETAR+	Physiotherapy ASPETAR+	The patients will follow the ASPETAR+ Hamstring Rehabilitation Protocol. ASPETAR+ is similar to ASPETAR, but consists of additional lengthening exercises which will be initiated early in the rehabilitation phase. ASPETAR+ consist of predefined rehabilitation stages including sports specific stages. Specific functional based criteria for progression will be utilized for each of the six rehabilitation stages. No pain provocation when performing the exercises will be allowed. The rehabilitation will be initiated as soon as possible after inclusion and the patients will be supervised by experienced physiotherapists in the Rehabilitation Department at Aspetar 3 to 5 days per week.

Primary Outcome Measures

Name	Time	Method
Time to Return to Sport (RTS)	After the initial injury, patients will be followed daily during working days for the duration of time until they return to RTS, with an expected average of 25 days up to 1 year	Number of days between initial injury and return to full unrestricted training and/or match play

Secondary Outcome Measures

Name	Time	Method
Re-injury within 2 months, 6 months and 12 months after RTS	The patients will be monitored by phone 2 months, 6 months and 12 months after RTS	In the event of a clinical suspicion of re-injury, the player will be advised to immediately call the primary investigator and consult a physician

Trial Locations

Locations (1)

Aspetar Orthopaedic and Sports Medicine Hospital; 🇶🇦 Doha, Qatar