Role of host factors in predicting antiviral response in chronic hepatitis C
Not Applicable
Completed
- Conditions
- Health Condition 1: null- Chronic hepatitis C patints
- Registration Number
- CTRI/2015/07/005992
- Lead Sponsor
- Institute of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 61
Inclusion Criteria
age 18-65 years, a chronic HCV genotype 1 and 4 infection with detectable HCV RNA for 6 month and no previous treatment for hepatitis C
Exclusion Criteria
Patients with advanced cirrhosis (Child-Pugh B or C), presence of hepatocellular carcinoma, human immunodeficiency and hepatitis B coinfection, , autoimmune liver disease , Wilson disease, hemochromatosis , α1-anti trypsin deficiency, concomitant use of medications known to affect serum vitamin D metabolism, and patients with active intravenous drug addiction
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Primary outcome was defined as sustained virologic response ,defined as undetectable HCV RNA 6 months after completion of therapyTimepoint: 6 month after completion of therapy
- Secondary Outcome Measures
Name Time Method Secondary outcome was defined as undetectable HCV RNA at 4,12 and 48 weeks of therapyTimepoint: 4,12,48 weeks