growth factor concentrate in knee osteoarthritis
Phase 3
- Conditions
- Health Condition 1: M170- Bilateral primary osteoarthritis of knee
- Registration Number
- CTRI/2023/04/051860
- Lead Sponsor
- teerthanker mahaveer medical college and research centre
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients who are satisfying the American College of Rheumatology (ACR) criteria for diagnosis of osteoarthritis knee.
Radiological findings of Grade II and III Osteoarthritis of the knee joint, according to the Kellgren-Lawrence scale.
Exclusion Criteria
Any malignancy.
Drug Abuse
Gouty Arthritis /inflammatory arthritis, Secondary Osteoarthritis
Active knee infection.
Patient Suffering from Anemia, Disorders of Bleeding
Rheumatoid Arthritis
Genu varum/valgum >5 degree
Uncontrolled Diabetes Mellitus
Ligamentous instability of knee (Tested by Clinical examination)
Osteoarthritis of any other joint
Patient in whom MRI is contraindicated.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method serum Coll2-1 levels <br/ ><br>knee MRITimepoint: baseline and 9 months
- Secondary Outcome Measures
Name Time Method visual analogue scale <br/ ><br>WOMAC scoreTimepoint: baseline <br/ ><br>6-month follow-up <br/ ><br>9-month follow-up