Evaluation of the effect of vitamin D on diabetic patients
Phase 2
- Conditions
- Type 2 diabetes with vitamin D deficiency.
- Registration Number
- IRCT20200616047795N1
- Lead Sponsor
- Birjand University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 68
Inclusion Criteria
The disease (diabetes) has already been confirmed by a specialist.
People with diabetes who have had diabetes for at least 5 years
The criterion for entering the diabetic group is HbA1C, which is outside the normal range.
Age range 50-65 years
The desire to participate in the study
Exclusion Criteria
Systemic diseases (rheumatoid arthritis ...) that can affect the results.
Cancer
Taking corticosteroids
Thyroid disease
Kidney diseases and adrenal glands
Liver diseases
Multivitamin consumption
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Vitamin D levels. Timepoint: First and after 8 weeks. Method of measurement: Vitamin D will be measured with a little luminescence technique.
- Secondary Outcome Measures
Name Time Method HDL, LDL, A1C hemoglobin levels, Nlrp3 gene, and oxidative stress status. Timepoint: First and after 8 weeks. Method of measurement: Tests (LDL, HDL) are performed with kits and enzymatic methods. The A1C Hb will be measured using the immunomturbidometry technique. However, PCR real-time techniques are used for genetic testing, as well as tests for oxidative stress status with TAC antioxidant kits by FRAP, Thiol group, and MDA by spectrophotometry.