Study on the clinical mechanism of synergistic effect of Benefiting Qi for strengthening resistance and rt-PA intravenous injection in patients with acute ischemic stroke

Phase 1

• Conditions: acute ischemic stroke

• Registration Number: ITMCTR2000004068
• Lead Sponsor: Dongfang Hospital Beijing University of Chinese Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1. Meet the diagnostic criteria for stroke in Chinese medicine and the diagnostic criteria for acute cerebral infarction in Western medicine;
2. Patients in accordance with TCM syndrome diagnosis and Qi deficiency syndrome;
3. Aged 18-90 years old, obtain informed consent of patients and family members;
4. Admission to the hospital within 6 hours of stroke symptoms and collect relevant clinical data;
5. The cranial MRI or CT did not clear the infarct area within 6 hours of the onset of stroke symptoms;
6. Patients who have not received anticoagulation therapy.

Exclusion Criteria

1. Exclude diseases such as cerebral hemorrhage, intracranial infection, intracranial tumors, and moyamoya disease, vasculitis, carotid artery dissection and other diseases that may cause stenosis and occlusion of large blood vessels;
2. Patients who are mentally abnormal or unconscious and cannot cooperate with the examination and physical examination;
3. Failure to complete CTA+CTP or head MRI for various reasons, or the subject refuses to investigate and follow-up;
4. Serious diseases of heart, lung, liver, kidney and other organs;
5. Patients with coagulopathy.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
IHSS score;