NCT06123624尚未招募不适用
Comparison of Desflurane and Sevoflurane on Remifentanil Requirement Using Analgesia Nociception Index-guided Anesthesia
Ajou University School of Medicine0 个研究点目标入组 78 人开始时间: 2023年11月27日最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 78
- 主要终点
- remifentanil requirement
研究概览
简要总结
The primary purpose of this study is to compare the desflurane and sevoflurane on remifentanil requirement using analgesia nociception index-guided anesthesia in patients undergoing spine surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 19 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Clinical diagnosis of herniated disc, injury of spinal cord, and neoplasm of spinal meninges
排除标准
- •Hyperbilirubinemia
- •Prior chronic pain
- •Prior opioid abuse
- •Cardiac arrythmia
研究组 & 干预措施
Desflurane group
Experimental
干预措施: Desflurane Inhalation Solution (Drug)
Sevoflurane group
Placebo Comparator
干预措施: Sevoflurane Inhalation Solution (Drug)
结局指标
主要结局
remifentanil requirement
时间窗: at time of the end of skin suture (up to 3 hours)
assessing the total dose of remifentanil administered from skin incision until skin suture
次要结局
未报告次要终点
研究者
Ji Eun Kim
Assistant professor
Ajou University School of Medicine
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