Desflurane and Sevoflurane on Remifentanil Requirement

Not Applicable

Not yet recruiting

• Conditions: Spinal Diseases
• Interventions: Drug: Desflurane Inhalation Solution; Drug: Sevoflurane Inhalation Solution

• Registration Number: NCT06123624
• Lead Sponsor: Ajou University School of Medicine

Brief Summary

The primary purpose of this study is to compare the desflurane and sevoflurane on remifentanil requirement using analgesia nociception index-guided anesthesia in patients undergoing spine surgery.

Detailed Description

Not available

Study Timeline

• Status Verified: 2023-11
• Study First Submitted: 2023-11-01
• Study First Submitted QC: 2023-11-07
• Last Update Submitted: 2023-11-07
• Study First Posted: 2023-11-09
• Last Update Posted: 2023-11-09
• Study Start: 2023-11-27
• Primary Completion: 2024-08-30
• Study Completion: 2024-08-30

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 78

Inclusion Criteria

• Clinical diagnosis of herniated disc, injury of spinal cord, and neoplasm of spinal meninges

Exclusion Criteria

• Hyperbilirubinemia
• Prior chronic pain
• Prior opioid abuse
• Cardiac arrythmia

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Desflurane group	Desflurane Inhalation Solution	-
Sevoflurane group	Sevoflurane Inhalation Solution	-

Primary Outcome Measures

Name	Time	Method
remifentanil requirement	at time of the end of skin suture (up to 3 hours)	assessing the total dose of remifentanil administered from skin incision until skin suture