Effect of Kurozu containing diet on health: a double-blind, randomized controlled trial with parallel group design.
- Conditions
- Healthy adults Prevention as follow, Obesity, dyslipidemia, hypertension, arteriosclerosis, diabetes mellitus, infarction or renal failure.
- Registration Number
- JPRN-UMIN000017706
- Lead Sponsor
- Kagoshima University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 40
Not provided
At the start of trial 1 Waist circumference, <85cm (men) or <90cm (women) 2 Blood pressure, over 140/90 mmHg, but a doctor concludes that the subject is not hypertension when the subject's blood pressure is under 147 mmHg. 3 Patient of hypertension 4 Patient of diabetes mellitus 5 Patient of dyslipidemia 6 Subjects lack cook skill or don't have any companions who have cook skill. 7 Subjects keep taking any supplements or medicines which affect glucose or lipid metabolism over 1 month 8 Subjects take any anti-obesity drugs or supplements. 9 Allergy to rice or rice koji. 10 Subjects keep taking over 10 ml of Kurozu or Kurozu supplements corresponding to 10 ml of Kurozu over 1 month. 11 Over 6.5% HbA1c (NGSP) 12 Over 126 mg/dl of fasting blood glucose 13 Over 150 mg/dl of triglyceride 14 Over 160 mg/dl of LDL-cholesterol If a doctor decides that the subject is needed medical treatment unless the value is <160 mg/dl, the subject is excluded. 15 Under 40 mg/dl of HDL-cholesterol
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method After 90 days intake of Kurozu or fake Kurozu containing diet. Waist circumference Serum TG
- Secondary Outcome Measures
Name Time Method After 90 days intake of Kurozu or fake Kurozu containing diet. LDL-cholesterol HDL-cholesterol Adiponectin (ratio of polymer and oligomer) Body weight, body fat weight, %body fat, lean body mass, muscle mass Basal metabolic rate, body mass index, total body water, quantity of bone mineral Blood pressure Cardio ankle vascular index Cva-a LF/HF-MEM Fasting blood glucose HbA1c (NGSP) Plasma anti oxidative power Plasma oxidation level, TBARS Plasma TNF-alpha Plasma CRP Plasma homocysteine Serum uric acid Plasma beta-Thromboglobulin Plasma plasminogen activator inhibitor-1 Plasma tissue-type plasminogen activator Plasma tissue factor pathway inhibitor Plasma tissue factor Plasma fibrinogen Serum creatinine and estimated glomerular filtration rate