A clinical trial to study the pain relief effect of two local anesthetic drugs ropivacaine and bupivacaine given to block the nerves located in abdominal wall after caesarean section.

Phase 4

Not yet recruiting

• Conditions: Encounter for cesarean delivery without indication,

• Registration Number: CTRI/2018/10/015979
• Lead Sponsor: Dr Aniket Kakade

Brief Summary

This is a randomized, double blind, parallel group trial to compare the efficacy of ropivacaine versus bupivacaine during surgical transversus abdominis plane [TAP]block for post-operative analgesia after caesarean section. Surgical TAP block is a established technique used for post operative analgesia. we plan to compare two drugs in 100 patients who require caesarean section. The post operative pain will be assessed by using the visual analogue scale [VAS] and the duration of analgesia in hours after giving the drug by TAP block will be assessed. Rescue analgesia will be administered to all those patients who complain of pain at VAS 3. The secondary outcome will be study of any side effects of the drugs.

Detailed Description

Not available

Study Timeline

• Study Start: 2018-01-11
• Last Update Posted: 2018-09-10

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: Female
• Target Recruitment: 100

Inclusion Criteria

all patients who require caesarean delivery.

Exclusion Criteria

Patient with ASA III or above Any allergy to used drug Local infection at the site of block Patients requiring vertical abdominal incision and upper segment caesarean section Patients requiring general anesthesia Height of patient less than 150 cms and more than 180 cms (as these patients will require a different dosage of spinal anaesthesia) Patients with thrombocytopenia.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Outcome Name: Post operative pain relief. To be assessed by Visual Analogue score [VAS]	Time Point: One hourly assessment for 8 hours

Secondary Outcome Measures

Name	Time	Method
Outcome Name: Side effects of the drugs	Time Points: Every hour assessment in post operative period for 24 hours.

Trial Locations

Locations (1)

Bharati Hospital & Research Center; 🇮🇳 Pune, MAHARASHTRA, India

Bharati Hospital & Research Center

🇮🇳Pune, MAHARASHTRA, India

Dr Aniket Kakade

Principal investigator

9850988568

aniket1kakade@gmail.com