Evaluate the effect of probiotics and phase 1 of periodontal treatment on patient with moderate to severe periodontitis
Not Applicable
- Conditions
- chronic periodontitis.Chronic periodontitis
- Registration Number
- IRCT201201258825N1
- Lead Sponsor
- Dental research center, Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
moderate to severe periodontitis and the presence of pockets more than 4mm. Patients must have the following parameters:
1.PPD>= 4mm; 2.CAL>=3mm and 3.bone loss >=3mm.
Exclusion criterion: 1.taking antibiotic over 3months ago; 2.immune deficiency disorders; 3.lactose intolerance and 4.taking immune suppressor drugs.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Gingival index. Timepoint: Day 0,14 and 28. Method of measurement: Prob.;Plaque index. Timepoint: Day 0,14 and 28. Method of measurement: Plaque staining.;Periodontal pocket depth. Timepoint: Day 0,14 and 28. Method of measurement: Prob.;Colony of Aggrebacter actinomycetcomitans. Timepoint: Day 0,14 and 28. Method of measurement: Colony count.;Bleeding on probing. Timepoint: Day 0,14 and 28. Method of measurement: Prob.;Periodontal disease index. Timepoint: Day 0,14 and 28. Method of measurement: Prob.
- Secondary Outcome Measures
Name Time Method