Measurement of in Vivo Mitochondrial Capacity in Infants
Terminated
- Conditions
- Healthy Infants
- Registration Number
- NCT03976596
- Lead Sponsor
- Pennington Biomedical Research Center
- Brief Summary
The overarching aim of this project is to determine the test re-test reliability of 31P-magnetic resonance spectroscopy measurements in infants. Primary endpoints include two separate measures of in vivo mitochondrial capacity (ATPmax) over a 1-10 day period to assess feasibility and reliability.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- All
- Target Recruitment
- 2
Inclusion Criteria
- healthy, full-term infant
- aged 14-28 days at Visit 1
- willingness of parents to be notified of incidental findings from study procedures
Exclusion Criteria
- born preterm
- implanted metal or electronic objects that render MRI unsafe
- unable to complete 2 clinic visits 1-10 days apart at Pennington Biomedical Research Center
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method In vivo mitochondrial capacity (ATPmax) 1 day In vivo mitochondrial capacity as measured by phosphorus magnetic resonance spectroscopy
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Pennington Biomedical Research Center
🇺🇸Baton Rouge, Louisiana, United States