Gene Polymorphism of Taste Receptors and Circulating Endocannabinoids in Normal Weight and Obese Subjects

Completed

• Conditions: Nutritional Physiological Phenomena

• Registration Number: NCT02729584
• Lead Sponsor: University of Cagliari

Brief Summary

The study aims at evaluating in normal weight and obese subjects those factors such as taste sensitivity and circulating endocannabinoids in influencing dietary choice and thereby lipid and energy metabolism in order to design personalized nutritional strategies.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-04
• Primary Completion: 2015-06
• Study Completion: 2015-09
• Status Verified: 2016-03
• Study First Submitted: 2016-03-23
• Study First Submitted QC: 2016-03-31
• Last Update Submitted: 2016-03-31
• Study First Posted: 2016-04-06
• Last Update Posted: 2016-04-06

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 110

Inclusion Criteria

• Body Mass Index (BMI), range for normal weight subjects 17.5-24.95, for obese subjects 29.6-52.20
• No intake of nutritional supplements for at least six months before the trial

Exclusion Criteria

• major diseases (diabetes, kidney disease, etc.),
• pregnancy or lactation;
• food allergies;
• the use of medications that interfere with taste or smell (e.g., steroids, antihistamines, certain antidepressants).

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Endocannabinoid plasma levels	1 year