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Study of microRNA in Pulmonary Tuberculosis

Not Applicable
Conditions
Health Condition 1: A150- Tuberculosis of lung
Registration Number
CTRI/2023/08/056740
Lead Sponsor
Dr Swathy Moorthy
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

cohort 1A : sputum positive Pulmonary Tuberculosis patients who will be classified as cavitatory type on chest X ray or CT scan

cohort 1B : sputum positive Pulmonary Tuberculosis patients who will be classified as non cavitatory type - no cavity on chest X ray or CT scan

Exclusion Criteria

age more than 60 and less than 18 years, current smoking or alcoholism, presence of any prior chronic medical illness, pregnancy, drug resistant tuberculosis, tuberculosis patients with HIV co-infection, previously treated with ATT or other active lung infection like community acquired pneumonia, on steroids, anti inflammatory, anti convulsants, anti cancer drugs

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
get the microRNA profile of sputum positive Pulmonary Tuberculosis patientsTimepoint: at the end of two years once all sample are collected analysis will be done
Secondary Outcome Measures
NameTimeMethod
identify the upregulated & downregulated microRNA in the sputum positive Pulmonary TuberculosisTimepoint: 3 years
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