Whole body muscle MRI in Myasthenia gravis
Recruiting
- Conditions
- MyastheniaMyasthenia gravis10029317
- Registration Number
- NL-OMON52030
- Lead Sponsor
- eids Universitair Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 55
Inclusion Criteria
- Definitive diagnosis of MG defined as the presence of serum autoantibodies
(anti-acetylcholine receptor [AChR], anti-muscle specific tyrosine kinase
[MuSK])
Exclusion Criteria
- Subjects who are not legally capable
- Subjects under the age of 18
- No (other) diagnosis of neuromuscular disease or chronic lesions to the
musculoskeletal system
- Contraindications to MRI scanning
- In healthy controls: the use of anabolic steroids
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The main study parameters are fat fraction, the muscle volume and the amount of<br /><br>positive T2-STIR lesions.</p><br>
- Secondary Outcome Measures
Name Time Method <p>The secondary study parameters are the scan protocol toleration by patients,<br /><br>the visibility of all muscles and the robustness of the quantitative data. </p><br>