In vivo studies on skin damage by Far-UVC at 233 nm in relation to melanin and age dependence and multiple irradiatio
Not Applicable
Recruiting
- Conditions
- healthy subjects
- Registration Number
- DRKS00030474
- Lead Sponsor
- Charité – Universitätsmedizin Berlin,Department of Dermatology, Venerology and Allergology,Center of Experimental and Applied Cutaneous Physiology (CCP)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 34
Inclusion Criteria
Over 18 years of age, no known skin diseases, skin type of I-IV (Fitzpatrick), informed about the aims of the study and the nature of the examinations, written informed consent to participate, no intensive sun exposure on the skin areas to be irradiated on the lower back/hip within the last 14 days prior to the irradiation date.
Exclusion Criteria
Minors, nursing mothers and women with known pregnancy, known skin diseases, skin type >IV (Fitzpatrick), intensive sun exposure on the skin areas to be irradiated on the lower back/hip within the last 14 days before the irradiation date, persons who cannot make decisions on their own responsibility
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Skin damage after Far UVC irradiation of 60 mJ/cm² 233 nm is equal to or less than ¼ MED UVB irradiation 24 h after irradiation. For this purpose, 3 mm biopsies are taken 24 h after irradiation and examined immunohistologically for DNA damage.
- Secondary Outcome Measures
Name Time Method