middle molecular clearance in citrate-based dialysis using a conventional vs. high-cutoff dialyzer

Not Applicable

Completed

• Conditions: N17; Acute renal failure

• Registration Number: DRKS00005254
• Lead Sponsor: niversität Leipzig

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2013-11-26
• Study Completion: 2015-05-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

acute dialysis dependent renal failure

Exclusion Criteria

therapeutic anticoagulation necessary in other indication; younger than 18 years; high risk of citrate accumulation (for instance acute liver failure); refusal of or contraindications for renal replacement therapie; predicted survival less than 48 h; pregnancy or lactation; member in other clinical trials; decline participation in study

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
ß2-Mikroglobulin Clearance after 1 h, 6 h, 12 h, 24 h und 48 h (estimated by serum levels before and after dialyzer)

Secondary Outcome Measures

Name	Time	Method
Clearance of Urea, Creatinin, Myoglobin and IL-6 after 1 h, 6 h, 12 h, 24 h und 48 h (estimated by serum levels before and after dialyzer)