Stress Echocardiography and Heart Computed Tomography (CT) Scan in Emergency Department Patients With Chest Pain

Not Applicable

Completed

• Conditions: Chest Pain; Angina; Coronary Artery Disease; Angina Pectoris
• Interventions: Procedure: Stress Echocardiography; Procedure: Coronary CT Angiography

• Registration Number: NCT01384448
• Lead Sponsor: Montefiore Medical Center

Brief Summary

The purpose of this study is to determine whether stress echocardiography or computed tomography (CT) of the heart is better at diagnosing emergency room chest pain patients to select appropriate candidates for hospitalization and further work-up.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2011-06-15
• Study First Submitted QC: 2011-06-27
• Study First Posted: 2011-06-29
• Study Start: 2011-08
• Primary Completion: 2016-02
• Study Completion: 2017-02
• Status Verified: 2017-03
• Last Update Submitted: 2018-10-09
• Last Update Posted: 2018-10-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 400

Inclusion Criteria

• Presentation to the Emergency Department with chest pain
• Low-to-intermediate risk of coronary disease per Diamond-Forrester criteria
• Free of known coronary artery disease

Exclusion Criteria

• Inability to undergo both stress echo or coronary CT for any reason
• Contraindication to intravenous iodinated contrast
• Dysrhythmia precluding EKG gating
• Heart rate greater than 60 with contraindication to beta blockers
• Administration of beta blockers within the last 12 hours
• Known severe cardiac valvular disease or pulmonary hypertension
• Stress echocardiography, coronary CT or catheterization within the last 6 months

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Initial Stress Echocardiography	Stress Echocardiography	-
Initial Coronary CT Angiography	Coronary CT Angiography	-

Primary Outcome Measures

Name	Time	Method
Hospital admission	30 days

Secondary Outcome Measures

Name	Time	Method
Emergency Department length of stay	30 days
Hospital length of stay	30 days
Estimated cost of initial care	30 days
Repeat visits to the Emergency Department	30 days and 1 year
Death	30 days and 1 year
Non-fatal myocardial infarction	30 days and 1 year

Trial Locations

Locations (1)

Montefiore Medical Center - Weiler / Einstein Division; 🇺🇸 Bronx, New York, United States