CTRI/2017/10/010292
Completed
未知
Safety and efficacy profile of systemic corticosteroids and isotretinoin versus systemic corticosteroids alone in cutaneous lichen planus- A hospital based prospective double blind placebo controlled comparative study
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Krishna Institute of Medical Sciences
- Enrollment
- 60
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •A.Must give written consent before any treatment commenced.
- •B.Must be diagnosed to be suffering from cutaneous lichen planus either by clinical examination or histopathology if required.
- •C.Must have generalised lichen planus involving minimum 20% body surface area or cases of palmoplantar lichen planus
- •D.Must stop any other modality of treatment, two months prior to the inclusion in study.
- •E.Must be able and willing, in the view of investigator, to comply all study procedure.
Exclusion Criteria
- •A. Patient having only oral lichen planus, genital lichen planus, nail lichen planus, follicular lichen planus, actinic lichen planus, lichen planus pigmentosus, lichen planus pemphigoides,
- •B. Patient with hypersensitivity to drug or patient intolerant to the study medication.
- •C. Pregnant and lactating patient.
- •D. Patient with unrealistic expectations.
- •E. Not willing for regular follow up.
- •F. Patient with clinically significant cardiovascular, haematological, pancreatic, metabolic neurological or any other laboratory anomaly, which in the judgement of investigator, would interfere in participation in study or proper evaluation.
- •G. Patient on any other systemic drugs therapy which in the judgement of investigator may interfere with interpretation of results.
- •H. Patient having history of tuberculosis or chest X\-ray showing evidence of any infective pathology.
- •I. Immunocompromised patients
Outcomes
Primary Outcomes
Not specified
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