Long Term Cardiovascular Disease Event Risk for Patients Undergoing Major Non-Cardiac
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Baseline assessment for calculating the pre-operative 10-year CVD event risk
研究概览
简要总结
The goal of this observational study is to learn whether the healthy lifestyle choices made around surgery can influence an individual's long term risk of developing cardiovascular disease. Patients will be observed 1-month prior to and 3-months following surgery to assess their risk of developing cardiovascular disease.
详细描述
Patients who experience a medical event are often motivated to improve their health by engaging in healthy lifestyle behaviors, such as improving their diet and beginning to exercise. For example, patients who are considered smokers prior to surgery may sometimes stop smoking following surgery. However, we are unsure of other changes following surgery. For example, we are unsure if surgery can initiate any changes in exercise and diet, and we are unsure if these changes can influence the risk of developing cardiovascular disease. Consistent and positive lifestyle changes will likely reduce an individual's risk of developing cardiovascular disease in the long term.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 45 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 45 - 75 years
- •Scheduled for intermediate- to high risk non-cardiac surgery (intra-thoracic or intra-abdominal surgery, all vascular surgery, intra-cranial neurosurgery, spine surgery)
- •Expected post-operative length of stay of at least two days, according to the surgeon's expectation
- •At least two of the following CVD risk factors:
- •History of: Hypertension, Diabetes, Coronary artery disease, Chronic heart failure, Chronic kidney disease, Cerebrovascular disease, Peripheral vascular disease.
- •Obesity (BMI >25 kg/m2), Current smoking, Poor exercise capacity (<4 METS)
排除标准
- •Currently participating in a CVD risk reduction program
- •Patient is scheduled to undergo transplant or has undergone emergency surgery
- •Life expectancy <1 year (palliative surgery)
- •Recent (<6 months) myocardial infarction or stroke
- •Surgery scheduled <1 month
- •Inability to effectively communicate
结局指标
主要结局
Baseline assessment for calculating the pre-operative 10-year CVD event risk
时间窗: 1 month before surgery
For the baseline assessment, the expected 10-year CVD event risk of each participant will be calculated according to the appropriate CVD event risk prediction score using blood tests, questionnaire to estimate an individual's functional capacity, blood pressure, heart rate and ECG.
Follow-up assessment for calculating the post-operative 10-year CVD event risk
时间窗: 3 months after surgery
For the follow-up assessment, the expected 10-year CVD event risk of each participant will be calculated according to the appropriate CVD event risk prediction score using blood tests, questionnaire to estimate an individual's functional capacity, blood pressure, heart rate and ECG.
次要结局
- Occurrence of Cardiovascular or Non-Cardiovascular event(30 days after surgery)