Lower Extremity Muscle and Function in the Elderly: Study 2

Tufts University1 site in 1 country52 target enrollmentSeptember 2009

ConditionsMobility Limitation

Overview

Phase: N/A
Intervention: Not specified
Conditions: Mobility Limitation
Sponsor: Tufts University
Enrollment: 52
Locations: 1
Primary Endpoint: Leg Extensor Muscle Power
Status: Completed
Last Updated: 7 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

This research study is looking to compare the effects of two uniquely different power training interventions (high force, lower velocity versus low force, high velocity) on changes in mobility status among older individuals at risk for mobility disability.

Registry

clinicaltrials.gov

Start Date

September 2009

End Date

October 2011

Last Updated

7 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Tufts University

Responsible Party

Principal Investigator

Roger A Fielding

Director and Senior Scientist, Professor of Nutrition, Jean Mayer USDA Human Nutrition Research Center on Aging.

Tufts University

Eligibility Criteria

Inclusion Criteria

•Male and Female 70-85 yrs
•Community dwelling
•Short Performance Battery Score \>9
•BMI range 19-32 kg/m2
•Willingness to be randomized and come the laboratory for 20 weeks.

Exclusion Criteria

•Acute or Terminal Illness
•MI in previous 6 months, symptomatic coronary artery disease or congestive heart failure.
•Upper or Lower extremity fracture in previous 6 months
•Uncontrolled hypertension (150/90mmHg)
•Neuromuscular diseases and drugs that affect neuromuscular function
•Hormone replacement therapy
•Participation in any regular endurance or resistance training exercise during previous 3 months

Outcomes

Primary Outcomes

Leg Extensor Muscle Power

Time Frame: Change from baseline to Week 16

Leg extensor muscle power measured on pneumatic strength testing equipment at a external force consistent with 70% of the participant maximum leg extensor strength.