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Lower Extremity Muscle and Function in the Elderly: Study 2

Not Applicable
Completed
Conditions
Mobility Limitation
Registration Number
NCT01614392
Lead Sponsor
Tufts University
Brief Summary

This research study is looking to compare the effects of two uniquely different power training interventions (high force, lower velocity versus low force, high velocity) on changes in mobility status among older individuals at risk for mobility disability.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
52
Inclusion Criteria
  • Male and Female 70-85 yrs
  • Community dwelling
  • Short Performance Battery Score >9
  • BMI range 19-32 kg/m2
  • Willingness to be randomized and come the laboratory for 20 weeks.
Exclusion Criteria
  • Acute or Terminal Illness
  • MI in previous 6 months, symptomatic coronary artery disease or congestive heart failure.
  • Upper or Lower extremity fracture in previous 6 months
  • Uncontrolled hypertension (150/90mmHg)
  • Neuromuscular diseases and drugs that affect neuromuscular function
  • Hormone replacement therapy
  • Participation in any regular endurance or resistance training exercise during previous 3 months

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Leg Extensor Muscle PowerChange from baseline to Week 16

Leg extensor muscle power measured on pneumatic strength testing equipment at a external force consistent with 70% of the participant maximum leg extensor strength.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Jean Mayer USDA Human Nutrition Research Center on Aging

🇺🇸

Boston, Massachusetts, United States

Jean Mayer USDA Human Nutrition Research Center on Aging
🇺🇸Boston, Massachusetts, United States

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