Lower Extremity Muscle and Function in the Elderly: Study 2

Not Applicable

Completed

• Conditions: Mobility Limitation
• Interventions: Behavioral: High velocity low force Power Training; Behavioral: Low velocity high force Power Training

• Registration Number: NCT01614392
• Lead Sponsor: Tufts University

Brief Summary

This research study is looking to compare the effects of two uniquely different power training interventions (high force, lower velocity versus low force, high velocity) on changes in mobility status among older individuals at risk for mobility disability.

Detailed Description

Not available

Study Timeline

• Study Start: 2009-09
• Study First Submitted: 2009-09-28
• Primary Completion: 2011-10
• Study Completion: 2011-10
• Study First Submitted QC: 2012-06-05
• Study First Posted: 2012-06-07
• Results First Submitted: 2017-05-26
• Status Verified: 2018-12
• Results First Submitted QC: 2018-12-06
• Last Update Submitted: 2018-12-06
• Results First Posted: 2018-12-10
• Last Update Posted: 2018-12-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 52

Inclusion Criteria

• Male and Female 70-85 yrs
• Community dwelling
• Short Performance Battery Score >9
• BMI range 19-32 kg/m2
• Willingness to be randomized and come the laboratory for 20 weeks.

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Exclusion Criteria

• Acute or Terminal Illness
• MI in previous 6 months, symptomatic coronary artery disease or congestive heart failure.
• Upper or Lower extremity fracture in previous 6 months
• Uncontrolled hypertension (150/90mmHg)
• Neuromuscular diseases and drugs that affect neuromuscular function
• Hormone replacement therapy
• Participation in any regular endurance or resistance training exercise during previous 3 months

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
High velocity low force Power Training	High velocity low force Power Training	Lower Extremity high velocity power training performed at lower external resistance (40% of the 1 repetition maximum muscle strength). Leg and knee extension exercises were performed twice per week (3 sets of each exercise consisting of 10 repetitions).
Low velocity high force Power Training	Low velocity high force Power Training	Lower extremity low velocity power training performed at high external resistance (70% of the 1 repetition maximum muscle strength). Leg and knee extension exercises were performed twice per week (3 sets of each exercise consisting of 10 repetitions).

Primary Outcome Measures

Name	Time	Method
Leg Extensor Muscle Power	Change from baseline to Week 16	Leg extensor muscle power measured on pneumatic strength testing equipment at a external force consistent with 70% of the participant maximum leg extensor strength.

Trial Locations

Locations (1)

Jean Mayer USDA Human Nutrition Research Center on Aging; 🇺🇸 Boston, Massachusetts, United States