Lower Extremity Muscle and Function in the Elderly: Study 2
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 52
- 试验地点
- 1
- 主要终点
- Leg Extensor Muscle Power
研究概览
简要总结
This research study is looking to compare the effects of two uniquely different power training interventions (high force, lower velocity versus low force, high velocity) on changes in mobility status among older individuals at risk for mobility disability.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 70 Years 至 85 Years（Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Male and Female 70-85 yrs
- •Community dwelling
- •Short Performance Battery Score >9
- •BMI range 19-32 kg/m2
- •Willingness to be randomized and come the laboratory for 20 weeks.
排除标准
- •Acute or Terminal Illness
- •MI in previous 6 months, symptomatic coronary artery disease or congestive heart failure.
- •Upper or Lower extremity fracture in previous 6 months
- •Uncontrolled hypertension (150/90mmHg)
- •Neuromuscular diseases and drugs that affect neuromuscular function
- •Hormone replacement therapy
- •Participation in any regular endurance or resistance training exercise during previous 3 months
研究组 & 干预措施
High velocity low force Power Training
Lower Extremity high velocity power training performed at lower external resistance (40% of the 1 repetition maximum muscle strength). Leg and knee extension exercises were performed twice per week (3 sets of each exercise consisting of 10 repetitions).
干预措施: High velocity low force Power Training (Behavioral)
Low velocity high force Power Training
Lower extremity low velocity power training performed at high external resistance (70% of the 1 repetition maximum muscle strength). Leg and knee extension exercises were performed twice per week (3 sets of each exercise consisting of 10 repetitions).
干预措施: Low velocity high force Power Training (Behavioral)
结局指标
主要结局
Leg Extensor Muscle Power
时间窗: Change from baseline to Week 16
Leg extensor muscle power measured on pneumatic strength testing equipment at a external force consistent with 70% of the participant maximum leg extensor strength.
次要结局
未报告次要终点
研究者
Roger A Fielding
Director and Senior Scientist, Professor of Nutrition, Jean Mayer USDA Human Nutrition Research Center on Aging.
Tufts University