How to recover from total knee arthroplasty with less pai
Not Applicable
Completed
- Conditions
- Degenerative knee joint osteoarthritisMusculoskeletal Diseases
- Registration Number
- ISRCTN14054997
- Lead Sponsor
- 301 Military Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 420
Inclusion Criteria
Patients undergoing primary, unilateral total knee arthroplasty (TKA) due to degenerative knee joint osteoarthritis.
Exclusion Criteria
1. Severe hypertension and cardiovascular diseases
2. Allergy to epinephrine and cold stimulation
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain at rest is measured by a 100 mm visual analogue scale (VAS), at 24, 48 and 72 hours after surgery.
- Secondary Outcome Measures
Name Time Method 1. Analgesic consumption is measured during hospitalisation. This depended on total doses of morphine used by PCA treatment, weak opioid analgesic and NSAID in every 12 hours<br>2. Drainage output was recorded and compared following extracting the drainage tube after 24 hours. Drainage output reflected dominant blood loss partly. Finally analyzed drainage output in this study resulted from deducting 50ml irrigation solution infused before surgery from recorded total output<br>3. Hemoglobin levels are measured 72 hours after surgery to find if levels have decreased<br>4. Knee joint girth as a reflection of swelling level and local inflammation was measured above 1 cm proximal to the upper border of the patella before operation, and at 48 and 96 hours after operation