Online Interpretation Bias Modification (CBM-I) in body dysmorphic disorder: a randomized-controlled trial

Phase 2

Conditions: Body dysmorphic disorder
F45.2
Hypochondriacal disorder

Registration Number: DRKS00012792

Lead Sponsor: AE Klinische Psychologie und PsychotherapieInstitut für Psychologie

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Enrolling by invitation

Sex: All

Target Recruitment: 60

Inclusion Criteria

primary diagnosis of body dysmorphic disorder based on current, at least moderate symptom severity (sum score of BDD-Y-BOCS = 20) and fulfillment of DSM-5 BDD criteria (procedure according to Wilhelm et al., 2014), age > 18 years, written consent, sufficient language fluency in German to understand tasks and questionnaires; access to the internet via PC/Laptop

Inclusion and exclusion criteria will be assessed via telephone and lab-based screening, those fulfilling criteria will be invited for participation.

Exclusion Criteria

current or previous diagnosis of substance abuse or dependence (excluding nicotine), current or previous diagnosis of schizophrenia, psychotic disorder, bipolar disorder based on SCID-I, BDI-II > 29 (i.e., severe levels of depression; Hautzinger et al., 2006); acute levels of suicidality; change in psychotropic medication within the last 8 weeks prior to study admittance; current on-going psychotherapeutic treatment

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Interpretation bias (Word Sentence Association Paradigm, WSAP; Interpretation Questionnaire; IQ),<br>body-dysmorphic symptom severity (BDD-Y-BOCS), insight (Brown Assessment of Belief Scale, BABS); functional impairment and clinical global impression (Clinical Global Impression Scale, CGIS; WHO Disability Assessment Schedule, WHO DAS 2.0) <br><br>Assessed at 5 Time Points:<br><br>Pre-Post (2 weeks)<br>FU 1 (1 week after post)<br>FU 2 (1 month after post)<br>FU 3 (3 months after post)

Secondary Outcome Measures

Name	Time	Method
Depressive symptom severity (BDI-II - Beck Depression Inventory-II), social anxiety symptom severity (Liebowitz Social Anxiety Scale, LSAS-SR), cognitive flexibility (WCST - Wisconsin Card Sorting Test, CFI - Cognitive Flexibility Inventory), implicit associative structure (Implicit Association Task, IAT); stress vulnerability (Mirror Gazing Task; Picture Taking Task) <br><br>Assessed at 2 Time Points:<br>Pre-Post (after 2 weeks).<br>WCST, CFI, Mirror Gazing Task, Picture Taking Task.<br><br>Assessed at 5 Time Points:<br>Pre-Post (after 2 weeks)<br>FU1 (1 week after post)<br>FU2 (4 weeks after post)<br>FU3 (3 months after post)<br>IAT, BDI-II und LSAS-SR.<br>