Fear Conditioning during specific conditions in Antisocial Adolescents: A Neuroimaging Study.
Recruiting
- Conditions
- Disrupted Behavior Disorder (DBD)Oppositional Defiant Disorder (ODD)Conduct Disorder (CD)
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 83
Inclusion Criteria
DBD:
- Male
Exclusion Criteria
DBD:
- Standard exclusion criteria (NIH) for MRI are the presence of pacemakers, aneurysm clips, artificial heart valves, ear implants, metal fragments or foreign objects in the eyes, skin or body.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Differental BOLD-response in the fear conditioning brain network during fear conditioning and during reward/punishment sensitivity.
- Secondary Outcome Measures
Name Time Method Fear conditioning level (CS+ vs CS- differentiation in skin conductance level, pupil dilatation, self-reported arousal and emotional valence). <br /><br>-Reward/punishment sensitivity (reaction time). <br /><br>-Risk taking behavior (number of pumps in risk taking behavior task). <br /><br>-Connectivity between brain structures through Diffusion Tensor Imaging (DTI) techniques and resting-state fMRI <br /><br>- brain structure through structural MRI.