Prevalence of Dementia and Delirium in Outpatient Clinics (DESTAN Trial)

Recruiting

• Conditions: Delirium Superimposed on Dementia; Delirium in Old Age; Delirium With Dementia
• Interventions: Diagnostic Test: Confussion assessment method (CAM); Diagnostic Test: Dementia diagnosis

• Registration Number: NCT04973709
• Lead Sponsor: Gulhane Training and Research Hospital

Brief Summary

The aim of this study is to assess the prevalence and etiologic risk factors of delirium in outpatient geriatric patients and also hospitalized patients.

Detailed Description

This study aimed to investigate the frequency of delirium and examines the association between delirium and other possible risk factors and prognostic factors (dementia etc.)

Study Timeline

• Study First Submitted: 2021-07-04
• Study First Submitted QC: 2021-07-21
• Study First Posted: 2021-07-22
• Study Start: 2021-08-05
• Status Verified: 2022-10
• Primary Completion: 2022-10-05
• Last Update Submitted: 2022-10-23
• Last Update Posted: 2022-10-25
• Study Completion: 2025-11-11

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 714

Inclusion Criteria

• We included all 65 years older patients who evaluated according to a comprehensive geriatric assessment that is consistently performed during admission to the outpatients' clinic of the hospital.

Exclusion Criteria

• Exclusion criteria were serious psychiatric disorders such as schizophrenia or major depression.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Delirium with dementia	Confussion assessment method (CAM)	Delirium was detected using the short form of the Confusion Assessment Method (CAM) both at admission and daily throughout the hospital stay. Cognitive status was determined using the Mini-Mental State Exam, Clinical Dementia Rating (CDR). Dementia was defined by a CDR score of 1. The primary independent variable was a composite of delirium and dementia diagnosis, and we examined the overlap by categorizing the cases into four groups: no delirium or dementia, dementia alone, delirium alone, and DSD.
Delirium with dementia	Dementia diagnosis	Delirium was detected using the short form of the Confusion Assessment Method (CAM) both at admission and daily throughout the hospital stay. Cognitive status was determined using the Mini-Mental State Exam, Clinical Dementia Rating (CDR). Dementia was defined by a CDR score of 1. The primary independent variable was a composite of delirium and dementia diagnosis, and we examined the overlap by categorizing the cases into four groups: no delirium or dementia, dementia alone, delirium alone, and DSD.
Delirium without Dementia	Confussion assessment method (CAM)	Delirium was detected using the short form of the Confusion Assessment Method (CAM) both at admission and daily throughout the hospital stay. Cognitive status was determined using the Mini-Mental State Exam, Clinical Dementia Rating (CDR). Dementia was defined by a CDR score of 1. The primary independent variable was a composite of delirium and dementia diagnosis, and we examined the overlap by categorizing the cases into four groups: no delirium or dementia, dementia alone, delirium alone, and DSD.
Dementia without Delirium	Dementia diagnosis	Delirium was detected using the short form of the Confusion Assessment Method (CAM) both at admission and daily throughout the hospital stay. Cognitive status was determined using the Mini-Mental State Exam, Clinical Dementia Rating (CDR). Dementia was defined by a CDR score of 1. The primary independent variable was a composite of delirium and dementia diagnosis, and we examined the overlap by categorizing the cases into four groups: no delirium or dementia, dementia alone, delirium alone, and DSD.

Primary Outcome Measures

Name	Time	Method
frequency of Mortality	1 year fellow-up	1st year mortality according to the electronic national data base

Trial Locations

Locations (1)

Gulhane training and research hospital; 🇹🇷 Ankara, Turkey