The Ketogenic Diet In Huntington’s Disease

Not Applicable

Withdrawn

• Conditions: Huntington's Disease; Neurological - Neurodegenerative diseases; Human Genetics and Inherited Disorders - Other human genetics and inherited disorders

• Registration Number: ACTRN12620000281998
• Lead Sponsor: Waikato Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-03-03
• Last Update Posted: 9 August 2022

Recruitment & Eligibility

• Status: Withdrawn
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

(1)Aged 20 to 80 years.
(2)Huntington’s confirmed by genetic diagnosis with 40 or more CAG repeats and definite motor manifestation as determined by a neurologist.
(3)Sufficient consent capacity (passing grade on the modified dementia Informed Consent questionnaire, defined as at least 70% of questions 1 to 10 correct and 100% of questions 11 to 14 correct on the first or second administration).
(4)BMI >18.5.
(5)A cohabiting study partner able and willing to follow the diet plan.

Exclusion Criteria

(1)Inability to speak or understand English.
(2)A concurrent medical or psychiatric condition that in the opinion of the investigators would make it difficult to complete the study.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in Unified Huntington's Disease Rating Scale (UHDRS) motor score from baseline to week 12[Baseline to week 12 (12 weeks)];Change in Unified Huntington's Disease Rating Scale (UHDRS) cognitive score from baseline to week 12[Baseline to week 12 (12 weeks)]