Investigation of the Effects of Inspiratory Muscle Training in Patients With Pulmonary Hypertension
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 24
- 试验地点
- 2
- 主要终点
- 6 minute walk test
研究概览
简要总结
This study aims to determine the possible effects of inspiratory muscle training on cardiovascular, respiratory, physical and psychosocial functions in patients with PH.
详细描述
Pulmonary Hypertension (PH) is a hemodynamic finding related to increase in pulmonary artery pressure. Because PH disease is a progressive, rare disease, it is important for this disease group to prolong the life span and to increase the quality of life and functional capacity. PH patients have been shown to have weakness in peripheral and respiratory muscles.
Patients will be randomly assigned to the inspiratory muscle training and control group. Inspiratory muscle training will be initiated in accordance with the patient at a range of 40-60%. İnspiratory muscle training will be given based on the assessments by the physiotherapist. Patients with PH who come to the routine outpatient clinic and volunteer will be included in the study. The first session will be the evaluation session and the 8-week inspiratory muscle training will be given, the other group will be the control group only. Dyspnoea, diaphragm thickness, pulmonary function, respiratory and peripheral muscle strength, blood pressure, arterial stiffness, physical activity, anxiety, depression and quality of life assessments will be repeated before and after the treatment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosis of Pulmonary Hypertension
- •According to the New York Heart Association functional class II - III
- •Cases receiving stable medication for 3 months
排除标准
- •Conditions which can limit the assessments
- •Severe ischemic heart disease
- •Acute cor pulmonale
结局指标
主要结局
6 minute walk test
时间窗: Change from Baseline at 8 weeks
functional capacity
次要结局
- Mouth pressures(Change from Baseline at 8 weeks)
- Modified Medical Research Council Dyspnea Scale(Change from Baseline at 8 weeks)
- Forced vital capacity(Change from Baseline at 8 weeks)
- Forced expiratory volume in 1 second(Change from Baseline at 8 weeks)
- Diaphragma thickness(Change from Baseline at 8 weeks)
- Levels of blood pressure(Change from Baseline at 8 weeks)
- Isometric muscle strength(Change from Baseline at 8 weeks)
- Arterial stiffness(Change from Baseline at 8 weeks)
- Upper extremity exercise capacity(Change from Baseline at 8 weeks)
- International Physical Activity Questionnaire-Short Form(Change from Baseline at 8 weeks)
- Fatigue Impact Scale(Change from Baseline at 8 weeks)
- Nottingham Health Profile(Change from Baseline at 8 weeks)
- Changes in Anxiety and Depression(Change from Baseline at 8 weeks)
- Changes in Dyspnea(Change from Baseline at 8 weeks)
研究者
Buse Ozcan Kahraman
Research Assistant
Dokuz Eylul University